Toxoplasmosis seroconversion is diagnosed on the presence of fluorescent antibodies. IgG level kinetics and presence of IgM at the Remington test are usually the points taken in consideration. But the Remington test can be false positive, or inadequate. The authors report their experience of gel filtration of sera in toxoplasmosis, and discuss the help that this method can be establishing diagnosis in the case of a positive Remington test.
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Background: Quadriceps dysfunction is ubiquitous after anterior cruciate ligament (ACL) reconstruction (ACLR). Addressing quadriceps dysfunction is crucial to improve function, reduce the reinjury risk, and maintain long-term knee health. While deficits specific to the quadriceps are well documented, less is known about the effect of an ACL injury on other lower extremity muscle groups.
View Article and Find Full Text PDFNurse Educ Today
December 2024
Faculty of Nursing, University of Calgary, Calgary, Alberta, Canada.
Aims: The aim of this review was to synthesize and appraise the available literature regarding academic success in undergraduate nursing education.
Design: We used Whittemore and Knafl's five-stage framework for integrative reviews. Toronto and Remington's step-by-step guide to integrative reviews provided practical guidance in the review process.
Schizophr Res
October 2024
Department of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands; Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, the Netherlands.
Background: Antipsychotic polypharmacy (APP) is frequently prescribed for schizophrenia-spectrum disorders. Despite the inconsistent findings on efficacy, APP may be beneficial for subgroups of psychotic patients. This meta-analysis of individual patient data investigated moderators of efficacy and tolerability of APP in adult patients with schizophrenia-spectrum disorders.
View Article and Find Full Text PDFInt J Nurs Stud Adv
December 2023
Clinical Health Sciences, University of South Australia, Adelaide, Australia.
Background: Workplace bullying, and violence within the midwifery profession, has been a well-documented concern in health literature since the early 1990's. However, contemporary research highlights that workplace bullying, and violence is often inflicted upon midwifery students. Workplace bullying, and violence has both short- and long-term effects on the student, including psychological trauma and poor mental health, loss of passion for the midwifery profession and absenteeism.
View Article and Find Full Text PDFPlants (Basel)
April 2024
Laboratoire de Génétique Biochimie et Biotechnologies Végétales, Faculté des Sciences de la Nature et de la Vie, Université Frères Mentouri Constantine 1, Constantine 25000, Algeria.
(1) Background: Due to the wide application in medicinal and pharmaceutical chemistry of flavonoid molecules, which are one of the most famous types of secondary plant metabolites, our work has come within the framework of bio-consulting to help in the identification of the molecule(s) responsible for the antibacterial effect which will be the active principle of a natural antibiotic developed from Algerian fir using bioinformatics tools. (2) Methods: The docking method was used to test the antiviral activity on SARS-CoV-2 virus and the antibacterial activity on Gram-positive and Gram-negative of 12 polyphenolic molecules present in the ethyl acetate and -butanol extracts of Numidian fir leaves, and identify the molecules responsible for these specific biological activities. (3) Results: The findings revealed that it is possible that two molecules, hyperoside and quercitrin, have a high capacity to inhibit SARS-CoV-2, and it is important to mention that they are the most quantitatively abundant molecules in the extract.
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