The isolation and characterization of many of the components of the avoparcin complex are described. A number of mild degradations products from this complex are similarly treated. Conditions for the analytical and preparative HPLC resolution of these materials are outlined.
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http://dx.doi.org/10.7164/antibiotics.36.1671 | DOI Listing |
Antibiotics (Basel)
January 2024
Department of Health Sciences, University "Magna Graecia" of Catanzaro, 88100 Catanzaro, Italy.
Trans Am Clin Climatol Assoc
March 2014
Department of Medicine, RhodeIsland Hospital, 593 Eddy Street, Providence, RI 02906, USA.
The human gastrointestinal tract is a complex environment of mutualistic associations. As bacteria form a major component of fecal content, the natural balance of the colon can be significantly altered by exposure to antimicrobial agents. However, the effects of antimicrobial therapy on fecal content are difficult to predict and can at times be quite surprising.
View Article and Find Full Text PDFInt J Food Microbiol
July 2009
Departamento de Agricultura y Alimentación, Universidad de La Rioja, Logroño, Spain.
Two-hundred-twenty-nine food samples of animal origin were tested to know the prevalence of vancomycin-resistant enterococci (VRE) after a decade of avoparcin ban as animal growth promoter in Spain. VRE with acquired mechanism of resistance were detected in 9 of these 229 samples (3.9%, obtained from chicken, veal and rabbit), and one VRE per food sample was further characterized.
View Article and Find Full Text PDFBiomed Chromatogr
December 2003
Department of Chemistry, Villanova University, Villanova, PA 19085-1699, USA.
Micellar electrokinetic chromatography (MEKC) was investigated as a technique for the separation and analysis of the following related glycopeptide antibiotics: alpha-avoparcin, beta-avoparcin, ristocetin A, ristocetin B and vancomycin. Sodium dodecyl sulfate (SDS) micelles were employed as the pseudostationary phase in conjunction with borate or CHES buffers at pH 9.2.
View Article and Find Full Text PDFAnal Biochem
March 2001
Department of Biomolecular Mass Spectrometry, Utrecht University, The Netherlands.
The conformational stability of vancomycin group antibiotics (i.e., vancomycin and avoparcin) in aqueous solution has been studied.
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