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The treatment strategy of patients with positive margins after cervical cold knife conization-A 7-year retrospective study in China.
Int J Gynaecol Obstet
January 2022
Department of Gynecology, Xiangya Hospital, Central South University, Changsha, China.
Objective: To explore treatment strategies for patients with positive margins after cervical cold knife conization (CKC) by estimating the risk of residual or recurrent CIN2 or worse (CIN2+).
Methods: A retrospective study included 569 patients receiving CKC for CIN3 in Xiangya Hospital from January 2013 to December 2017. Demographic characteristics and test results were obtained before CKC, after CKC, at 6, 12, and 24 months, then annually thereafter.
The risk factors of residual lesions and recurrence of the high-grade cervical intraepithelial lesions (HSIL) patients with positive-margin after conization.
Medicine (Baltimore)
October 2018
Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University.
Article Synopsis
- The study aimed to identify risk factors for residual lesions and recurrence in high-grade cervical intraepithelial lesions (HSIL) patients with positive margins after undergoing cervical conization.
- It analyzed data from 218 patients who underwent either cold knife conization (CKC) or loop electrosurgical excisional procedure (LEEP) from 2013 to 2016, finding significant correlations between factors like age, menopausal status, and HPV infection with residual disease rates.
- The study concluded that while LEEP and CKC are equally effective regarding recurrence rates, HPV infection and glandular involvement were significant factors in recurrence, suggesting further research is necessary to validate these findings.*
[Conization--a method for the diagnosis and treatment of cervix uteri changes].
Akush Ginekol (Sofiia)
February 1984
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