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Supramolecular Combination Chemotherapy: Directly Inducing Immunogenic Cell Death To Inhibit Tumor Metastasis via Host-Guest Interactions.
ACS Appl Mater Interfaces
January 2025
Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, P. R. China.
Tumor metastasis is a difficult clinical problem to solve due to tumor heterogeneity and the emergence of antiapoptotic clones driven by tumor evolution. Clinical combination chemotherapy remains a standard treatment for solid metastasis tumors but with worse treatment efficiency. It is worth exploring a high-efficiency and low-side-effect therapeutic method to solve solid metastases.
View Article and Find Full Text PDFFamily Husbandry in the Tropical Island of Mayotte: Struggling for Autonomy from Production to Sanitary Problems.
Animals (Basel)
November 2024
MayBiotech SARL, 8 Rue de la Gendarmerie, 97620 Bouéni, France.
Article Synopsis
- Mayotte, a small tropical island in the Comoros, has become a French department but relies heavily on imported food, highlighting the need for local livestock farming development.
- Interviews with 15 farmers revealed major challenges, including limited land access for raising animals, water scarcity, and inadequate road infrastructure impacting farm operations.
- Additional obstacles include dependence on imported animal feed and livestock, lack of organized local food systems, and financial constraints; while animal health issues are present, farmers tend to favor traditional medicine over seeking veterinary care.
In vitro cytotoxicity assessment of different solvents used in pesticide dilution.
J Environ Sci Health B
December 2024
Centre of Research and Development of Environmental Protection, Biological Institute, APTA, São Paulo, Brazil.
Pesticides are diluted in products called solvents for spraying fields and for cell viability studies. This study aimed to determine whether pesticide solvents can alter the toxicity of endosulfan and Vero cell viability. Thus, the cytotoxicity of some diluents commonly used in pesticide solutions was evaluated by the neutral red incorporation technique and cell growth.
View Article and Find Full Text PDFMolecular identification of the most frequent pathotypes of in calves with diarrhoea in the Cajamarca region of Peru.
Open Vet J
September 2024
Laboratorio de Biotecnología en Sanidad Animal, Estación Experimental Baños del Inca, Dirección de Desarrollo Tecnológico Agrario, Instituto Nacional de Innovación Agraria (INIA), Baños del Inca, Cajamarca, Perú.
Background: Colibacillosis caused by causes significant economic losses in the livestock sector worldwide and is one of the calves' leading causes of diarrhea.
Aim: This study aimed to identify the most frequent molecularly pathotypes in calves with diarrhea in six provinces of the Cajamarca region in the northern highlands of Peru.
Methods: Twenty-eight herds of dairy cattle under a semi-intensive rearing system were evaluated; 95 samples were isolated from calves with diarrhea up to the first month of life, 62 males and 33 females, during the rainy season.
Statistical assessment for reusing permeate from dewatering water treatment sludge process: more sustainability in environmental sanitation.
Environ Monit Assess
October 2024
Research Group for Optimization of Analytical Technologies Applied to Environmental and Sanitary Samples (GOTAS), School of Technology, Universidade Estadual de Campinas, Limeira, SP, 13484-332, Brazil.
Sludge from water treatment plants (WTPs) is usually processed by physicochemical clarification followed by thickening, which results in the production of an effluent from dewatering/drying sludge processes that can potentially impact the environment. This paper assessed the viability of employing sludge dewatering water from a water treatment sludge plant (WTSP) in São Paulo State, Brazil, for reuse purposes. Water quality variables were monitored in the effluent and receiving stream.
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