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White Matter Fiber Bundle Alterations Correlate with Gait and Cognitive Impairments in Parkinson's Disease based on HARDI Data.
Curr Med Imaging
January 2025
Department of Radiology, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong An Road, Xicheng District, Beijing 100050, China.
Background: The neuroanatomical basis of white matter fiber tracts in gait impairments in individuals suffering from Parkinson's Disease (PD) is unclear.
Methods: Twenty-four individuals living with PD and 29 Healthy Controls (HCs) were included. For each participant, two-shell High Angular Resolution Diffusion Imaging (HARDI) and high-resolution 3D structural images were acquired using the 3T MRI.
Cinacalcet Improves Erythropoietin Resistance in Patients with Secondary Hyperparathyroidism Receiving Dialysis Treatment.
Curr Pharm Des
January 2025
Department of Nephrology, the Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.
Introduction: Chronic Kidney Disease (CKD) is recognized as a major global public health problem. Dialysis is the mainstay of treatment for patients with end-stage renal disease and can prolong survival in patients with CKD. As patient survival increases, the treatment of complications becomes more important.
View Article and Find Full Text PDFEfficacy and safety of triple hormone receptor agonist retatrutide for the management of obesity: a systematic review and meta-analysis.
Expert Rev Clin Pharmacol
January 2025
Department of Internal Medicine, HIND Institute of Medical Sciences, Barabanki, India.
Introduction: Retatrutide is a novel triple hormone receptor agonist which has shown great promise in tackling obesity in preliminary trials. We did this systematic review and meta-analysis to pool the results of all available trials and ascertain its safety and efficacy in the treatment of obesity.
Material And Methods: A literature search was conducted in PubMed, Cochrane Central and Embase using appropriate search terms and randomized control trials (RCTs) were identified which reported the safety and efficacy of retatrutide.
Ellagitannins from Pomegranate Flower with Whitening and Anti-skin Photoaging Effect.
Chem Biodivers
January 2025
Yatsen Global Innovation R&D Center, Yatsen Global Innovation R&D Center, No. 11 Building, No. 210, Wenshui Road, Jingan District, Shanghai, CHINA.
A new depside glucoside rosarugoside E (1), together with four known compounds punicalagin (2), corilagin (3), granatin B (4) and ellagic acid (5) were isolated from the ethanol extract of pomegranate (Punica granatum L.) flower. Their structures were identified based on careful analysis of various spectral data including UV, IR, HR-ESI-MS, 1D and 2D NMR.
View Article and Find Full Text PDFSpatiotemporal Mapping of Ultrafine Particle Fluxes in an Office HVAC System with a Diffusion Charger Sensor Array.
ACS EST Air
January 2025
Lyles School of Civil & Construction Engineering, Purdue University, West Lafayette, Indiana 47907, United States.
Commercial HVAC systems intended to mitigate indoor air pollution are operated based on standards that exclude aerosols with smaller diameters, such as ultrafine particles (UFPs, D ≤ 100 nm), which dominate a large proportion of indoor and outdoor number-based particle size distributions. UFPs generated from occupant activities or infiltrating from the outdoors can be recirculated and accumulate indoors when they are not successfully filtered by an air handling unit. Monitoring UFPs in real occupied environments is vital to understanding these source and mitigation dynamics, but capturing their rapid transience across multiple locations can be challenging due to high-cost instrumentation.
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