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Combined Phacoemulsification, Goniosynechialysis and Ab Interno Trabeculectomy in Primary Angle-closure Glaucoma: Long-term Results.
Int J Med Sci
January 2025
Department of Ophthalmology, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, China, 100044.
This research was designed to evaluate the efficacy and safety of ab-interno trabeculectomy (Trabectome and Kahook Dual Blade) combined with phacoemulsification, intraocular lens implantation, and goniosynechialysis in eyes with primary angle-closure glaucoma. A total of 47 patients were included in the study and all the patients received the combined surgery. Intraocular pressure, anti-glaucoma medications, best-corrected visual acuity, and the number of peripheral anterior synechiae quadrants were recorded at baseline and at various time points after surgery.
View Article and Find Full Text PDFAdvancing Glaucoma Treatment During Pregnancy and Breastfeeding: Contemporary Management Strategies and Prospective Therapeutic Developments.
Biomedicines
November 2024
Department of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.
The management of glaucoma in pregnancy and breastfeeding requires a careful evaluation of treatment choices to guarantee the well-being of both the mother and the developing fetus. This review explores the intricacies of controlling glaucoma in pregnant and breastfeeding women, including a comprehensive overview of existing glaucoma treatment methods, clinical guidelines, and future therapeutic approaches. The efficacy and safety profiles of traditional treatment approaches, such as topical and systemic medicines and surgical treatments, are evaluated specifically about their use during pregnancy and breastfeeding.
View Article and Find Full Text PDFCurrent trends and advancements in utilizing endoscopic cyclophotocoagulation for the Treatment of Glaucoma.
Lasers Med Sci
November 2024
Shenzhen Eye Institute, Shenzhen Eye Hospital, Jinan University, Shenzhen, China.
Article Synopsis
- * Endoscopic cyclophotocoagulation (ECP) is a key treatment method that works by reducing the production of aqueous humor through the coagulation of the ciliary body, and has been in use since the 1990s.
- * The review discusses the technology used in ECP, its effectiveness compared to other treatments, its current clinical use, possible postoperative complications, and how ECP’s role in glaucoma treatment is expected to grow and adapt with new advancements.
Self-assembled latanoprost loaded soluplus nanomicelles as an ophthalmic drug delivery system for the management of glaucoma.
Sci Rep
November 2024
Department of Pharmacy, University of Peshawar, Peshawar, 25000, Pakistan.
Glaucoma, a leading cause of blindness due to elevated intraocular pressure (IOP), is managed with medications like latanoprost (LAT), a prostaglandin analogue, to enhance aqueous outflow. Despite the challenge posed by eye anatomy and tear dynamics, effective ocular bioavailability via topical administration remains elusive. This study aims to optimize self-assembled nanomicelles incorporating LAT, an anti-glaucoma drug, belonging to BCS Class II (low solubility and high permeability) via a two-level, two-factor full factorial design, the nanomicelles were formulated via direct dissolution method and validated using design of expert.
View Article and Find Full Text PDFEarly Results of PRESERFLO TM MicroShunt for Primary Open-angle Glaucoma in Caucasian Patients.
J Glaucoma
October 2024
Department of Ophthalmology, Medical Faculty Carl Gustav Carus, Technische Universität, Fetscherstrasse 74, 01307 Dresden, Germany.
Precis: The PRESERFLO MicroShunt effectively lowered intraocular pressure in primary high and normal pressure open-angle glaucoma.
Purpose: To evaluate the efficacy and safety of the PRESERFLOTM MicroShunt in patients with primary open-angle glaucoma (POAG) and the two variants high (HPG) and normal pressure glaucoma (NPG) after one year.
Methods: Single-center prospective interventional case series consecutively including eyes of White/European patients with POAG, who received the PRESERFLOTM MicroShunt as a primary and stand-alone glaucoma intervention.
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