Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
The radionuclide technique was used to study regional microcirculation in 139 patients with diabetic angiopathies of the lower limbs. All the examined demonstrated impairment of the muscular bloodflow, that increased depending on the disease stage and diabetes mellitus standing. No differences were recorded in the degree of bloodflow impairment in the muscles of patients treated with sulfanilurea drugs and insulin. Comparison of the degree of changes in the muscular bloodflow in diabetic angiopathies of the lower limbs and atherosclerosis obliterans of lower limb vessels in subjects without diabetes mellitus demonstrated that microcirculation in the former group patients was affected to a greater measure. It is desirable that the complex of therapeutic measures should include drugs that improve microcirculation at the early stages of the management of patients with diabetic angiopathies of the lower limbs.
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