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The Frequency of Mediastinal Lymph Node Calcification in Sarcoidosis Patients and the Influencing Factors.
Medicina (Kaunas)
December 2024
Department of Respiratory Disease, Cukurova University Faculty of Medicine, Yüreğir, Adana 01250, Turkey.
: This study investigates the prevalence of calcification in mediastinal lymph nodes among sarcoidosis patients and the influencing factors. Sarcoidosis is a multisystemic inflammatory disease characterized by non-caseating epithelioid granulomas. Bilateral hilar lymphadenopathy (LAP) is the most common radiographic finding, with studies showing a correlation between the frequency of lymph node calcification and disease duration, with a frequency of 3% relating to a duration of 5 years and a frequency of 20% relating to one of 10 years.
View Article and Find Full Text PDFDacryoadenitis as a Rare Initial Presentation in a Patient with Suspected Crest Syndrome.
Eur J Case Rep Intern Med
September 2024
Department of Ophthalmology, Sawai Man Singh Medical College, Jaipur, India.
Article Synopsis
- Systemic sclerosis (SSc) is a rare disease that can affect different parts of the body, and this case is about a 51-year-old woman who had swelling in her eyelid.
- Doctors found she had an enlarged lacrimal gland and inflammatory symptoms that didn’t get better with regular treatments, which led them to explore further possible conditions.
- This case is important because it shows that SSc, specifically CREST syndrome, can have unusual symptoms like swelling in the eyes, and doctors need to think about different diagnoses when they see such signs.
A Rare Case of Isolated Extrapulmonary Sarcoidosis With Renal Involvement Sans Pulmonary Findings: Diagnostic Challenges and Clinical Insights.
Cureus
August 2024
Nephrology, Wellstar Spalding Medical Center, Griffin, USA.
Article Synopsis
- Sarcoidosis is an unknown multi-system disease characterized by granulomas, primarily seen in the lungs but can also cause lymph node issues and rarely affects the kidneys.
- A case study of a 59-year-old man reveals that despite normal chest imaging, he was diagnosed with sarcoidosis due to symptoms like renal failure and the presence of noncaseating granulomas in a skin biopsy.
- The report emphasizes that sarcoidosis can present without lung symptoms, suggesting that doctors should consider it when diagnosing unexplained high calcium levels, even in the absence of typical lung or skin signs.
Polymorphous Cutaneous Sarcoidosis With Excellent Response to Minocycline.
Cureus
October 2023
Dermatology, Rush University Medical Center, Chicago, USA.
Sarcoidosis is notorious for producing a wide variety of skin lesions, which are categorized as either specific or nonspecific. The specific lesions include primary morphologies ranging from micropapules to subcutaneous nodules. Nonspecific skin lesions include associated conditions like erythema nodosum, calcinosis cutis, and prurigo.
View Article and Find Full Text PDFNephrocalcinosis in a Transplanted Kidney: A New Sign of Chronic Tacrolimus Nephrotoxicity.
Saudi J Kidney Dis Transpl
November 2022
Department of Radiology, Qutaina Medical Center, Kuwait City, Kuwait.
Article Synopsis
- Calcineurin inhibitors, like tacrolimus, are strong immunosuppressants used in organ transplants that can lead to kidney issues such as reduced filtration and chronic fibrosis.
- A case study highlights a kidney transplant patient experiencing allograft failure with nephrocalcinosis, which was not due to common causes like hyperparathyroidism or excessive calcium levels.
- Improvement in the patient’s renal function after stopping tacrolimus suggests that nephrocalcinosis may be a sign of chronic kidney damage related to this medication.
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