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Influence of intravenous lidocaine infusion on haemodynamic response to tracheal intubation and metabolic-hormonal responses during laparoscopic procedures in children: a randomised controlled trial.
BMC Anesthesiol
January 2025
Department of Paediatric Anaesthesiology and Intensive Care, Medical University of Warsaw University Clinical Centre, ul. Żwirki i Wigury 63A, Warsaw, 02-091, Poland.
Background: Lidocaine, a widely used local anaesthetic, also serves as an adjuvant in pain management. However, its use in children is off-label. This study aimed to determine if intravenous lidocaine alleviates the haemodynamic, metabolic, and hormonal responses to intubation and laparoscopic surgery in children.
View Article and Find Full Text PDFChronic Pruritus: A Review.
JAMA
June 2024
Miami Itch Center, Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida.
Article Synopsis
- - Chronic pruritus, or long-term itch lasting 6 weeks or more, affects about 22% of people, leading to poor sleep and decreased quality of life, though it represents only 1% of doctor visits.
- - The condition can be classified into inflammatory (60% of cases), neuropathic (25%), or other causes (15%), with common inflammatory triggers being eczema and psoriasis, while neuropathic issues may arise from nerve dysfunction.
- - Diagnosis often involves thorough history-taking and lab tests, with initial treatments typically being topical anti-inflammatory medications; if these fail, referral to a specialist or systemic treatments may be necessary.
Manual Reduction of Strangulated Internal Hemorrhoids Using Sugar: A Case Report.
Cureus
March 2024
Gastroenterological Surgery, Koga Community Hospital, Yaizu, JPN.
Emergency hemorrhoidectomy for strangulated internal hemorrhoids should be avoided when possible. Manual reductions can relieve pain and prevent the need for emergency surgery. Herein, we present a 51-year-old female patient.
View Article and Find Full Text PDFEvaluation of pharmacological alternatives to reduce the pain and discomfort produced by electroejaculation in rams.
Reprod Domest Anim
January 2024
Santo Amaro University (UNISA), São Paulo, São Paulo, Brazil.
Electroejaculation (EE) represents the main technique for semen collection from domestic and wild animals independently of libido. However, the technique is associated with intense involuntary muscle contractions, vocalization, ataxia and lying down, caused by the electric stimulation of the nerves in the caudal epigastric region. These clinical manifestations represent important indicators of discomfort.
View Article and Find Full Text PDFEvaluation of the efficacy and safety of an innovative flavonoid lotion in patients with haemorrhoid: a randomised clinical trial.
BMJ Open Gastroenterol
August 2023
Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL), Clinical Sciences Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
Objective: Haemorrhoids are one of the most common gastrointestinal and anal diseases. In olive oil and honey propolis, flavonoids have beneficial effects on improving vascular function and decreasing vascular resistance. In this study, we aimed to produce a combination of these two substances in the form of lotions and assess their healing and side effects in comparison with routine treatment, anti-haemorrhoid ointment (containing hydrocortisone and lidocaine).
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