The preparation of some homologues of 2-(4-cyclohexylphenyl)-3-hydroxypropionic acid, the separation of the diastereomeric race-mates, their attribution to erythro and threo series, and the optical resolution of the enantiomers are described. The optical antipodes were screened for acute toxicity, as well as for antiinflammatory and analgesic activity.

Download full-text PDF

Source

Publication Analysis

Top Keywords

[nonsteroidal anti-inflammatory
4
anti-inflammatory agents
4
agents xiii
4
xiii 4-cyclohexylphenylhydroxyalkanoic
4
4-cyclohexylphenylhydroxyalkanoic acids]
4
acids] preparation
4
preparation homologues
4
homologues 2-4-cyclohexylphenyl-3-hydroxypropionic
4
2-4-cyclohexylphenyl-3-hydroxypropionic acid
4
acid separation
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!