A survey of three indices of ventilatory capacity, forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and peak expiratory flow rate (PEFR), was undertaken on 3490 Chinese inhabitants of Hong Kong. Nomograms have been constructed for the prediction of these three indices for subjects between the ages of 5 and 75 years.
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Transplant Direct
February 2025
Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Background: Baseline lung allograft dysfunction (BLAD) after lung transplant is associated with an increased risk of dying, but the association with health-related quality of life (HRQL) and exercise capacity is not known. We hypothesized that BLAD would be associated with reduced HRQL and 6-min walk distance (6MWD) at 1 y post-lung transplant.
Methods: We analyzed patients who underwent lung transplants in our program from 2004 to 2018 who completed 1-y 36-item Short Form (SF-36) questionnaire and 6MWD testing.
Int J Chron Obstruct Pulmon Dis
January 2025
Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, People's Republic of China.
Background: Both sensitization and mucus plugs are associated with poor clinical outcomes in COPD. However, little is known about the association between hypersensitivity and mucus plugging in patients with COPD.
Methods: We retrospectively enrolled COPD patients who had visited Peking University Third Hospital and received measurement of the specific IgE ( sIgE) from Oct 1, 2018 to Sep 30, 2023.
Int J Chron Obstruct Pulmon Dis
January 2025
Department of Obstetrics and Gynecology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Purpose: Airway disease is the main pathological basis of chronic obstructive pulmonary disease (COPD), but the underlying mechanisms are unknown. Bone morphogenetic protein-7 (BMP7) is a multi-functional growth factor that belongs to the transforming growth factor superfamily, which affects the regulation of proliferation, differentiation, and apoptosis. Previous research has shown that BMP7 is highly expressed in the airway epithelia of patients with COPD, but its role in airway disease has not been fully elucidated.
View Article and Find Full Text PDFJSLS
January 2025
Department of Thoracic and Cardiovascular Surgery, Wuhu Hospital Affiliated to East China Normal University (Wuhu No. 2 People's Hospital), Wuhu, Anhui, China. (Drs. Wang, Geng, Wu, and Tao).
Objective: To explore a model suitable for enhanced recovery after surgery (ERAS) for elderly patients with lung cancer in this region.
Methods: A total of 200 elderly patients with lung cancer who were admitted to our department and received thoracoscopic surgery from January 1, 2020, to December 31, 2021, were enrolled as observation subjects and were randomly assigned to an ERAS group (100 cases) and a control group (100 cases). All patients were aware of and agreed to enter the study, and the protocols were approved by the hospital ethics committee (2021 Medical Ethics Review 26).
Occup Med (Lond)
January 2025
Department of Public Health and Nursing, HUNT Research Centre, NTNU, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Background: The association between occupational titles and lung function has mostly been examined through cross-sectional studies. Preventive measures are expected to mitigate adverse effects; hence, updated estimates are necessary.
Aims: To study change in lung function measured by spirometry across occupations.
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