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Protective role of calcium-based agents in dental bleaching gels: insights from a systematic review and meta-analysis of clinical and laboratory evidence.
Clin Oral Investig
March 2025
Department of Preventive and Restorative Dentistry, Araçatuba School of Dentistry, São Paulo State University (UNESP), Araçatuba, SP, Brazil.
Objectives: This systematic review and meta-analysis (SRM) evaluated the effect of incorporating calcium-based bioactive agents in bleaching gels on dental structure preservation and whitening efficacy.
Methods: A comprehensive search was conducted across databases up to November 2024. Two independent reviewers screened and selected clinical trials and in vitro studies evaluating the effects of calcium-based bioactive agents in bleaching gels, following predefined PICO criteria.
[Guidelines for the prevention and management of bronchial asthma (2024 edition)].
Zhonghua Jie He He Hu Xi Za Zhi
March 2025
Bronchial asthma (asthma) is a common chronic respiratory disease. Standardized diagnosis, treatment and effective clinical management are critical to improving asthma control, improving patients' quality of life, and reducing the disease burden. Based on the latest evidence-based research from both domestic and international references, the Asthma Group of the Chinese Thoracic Society has revised the " ()".
View Article and Find Full Text PDFDesensitization to colecalciferol in 18 patients with immediate hypersensitivity reactions.
World Allergy Organ J
February 2025
University of Health Sciences Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, Chest Diseases Clinic, Istanbul, Turkey.
Introduction: Hypersensitivity reactions (HSRs) to colecalciferol (vitamin D) have been rarely reported and the mechanism is unknown. As an alternative treatment was not recommended for vitamin D deficiency, a desensitization protocol with colecalciferol can be performed. We found that there is no standard desensitization protocol for vitamin D.
View Article and Find Full Text PDFEffect of an experimental pregabalin gel on dental sensitivity and color change after bleaching with 35% hydrogen peroxide: a randomized clinical trial.
Clin Oral Investig
March 2025
Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Pará, Av. Augusto Corrêa, nº 01, Belém, 66.075-110, PA, Brazil.
Objective: This clinical study evaluated an experimental pregabalin (PG) gel in reducing dental sensitivity (DS) and color change after dental bleaching.
Materials And Methods: Seventy-five volunteers were selected and randomized into three groups: GPG (10% pregabalin gel), GKF (5% potassium nitrate and 2% sodium fluoride), and GP (placebo gel). Prior to the bleaching treatment, GPG and GKF received applications of the respective desensitizing gels for 10 min.
Hypersensitivity reactions (HRs) to iron agents are increasing in parallel with increased use of iron preparations. We aimed to evaluate the clinical features and our previous desensitization protocol in patients with immediate hypersensitivity reactions (IHR) to iron agents. We screened the medical records of 96 patients with a history of IHRs to oral or intravenous (IV) iron agents.
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