The diagnosis of the primary hyperparathyroidism is, as it is demonstrated at the example of a female patient, up to now always made very late. It is referred to the importance of modern screening methods which are suitable to improve the early diagnosis and to reduce the still high rate of complications.
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Brown Tumour As An Unusual But Preventable Cause Of Spinal Cord Compression: Case Report And Literature Review.
J Pak Med Assoc
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Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Brown tumour is an infrequent, focal, and benign osteolytic lesion which is a consequence of abnormal bone metabolism in hyperparathyroidism (both primary and secondary). It is also known as Osteoclastoma. In the present era, we rarely encounter skeletal disease caused by primary hyperparathyroidism.
View Article and Find Full Text PDFOutcomes of Subtotal Parathyroidectomy Versus Total Parathyroidectomy With Autotransplantation for Tertiary Hyperparathyroidism: Multi-institutional Study.
Ann Surg
October 2021
Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University, School of Medicine, New Orleans, Louisiana.
Objectives: Due to the paucity of data and controversy regarding the preferred surgical approach for managing tertiary HPT, we sought to investigate the outcomes of different surgical approaches in managing this challenging disease.
Methods: We performed a multi-center retrospective study to include patients with tertiary HPT who underwent STPX or total parathyroidectomy with autotransplantation (TPX-A).
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Anesthetic considerations in hyperparathyroid crisis: A case report.
Medicine (Baltimore)
January 2021
Department of Anesthesiology, Peking University First Hospital, Beijing, China.
Introduction: Hyperparathyroid crisis is a rare and potentially life-threatening complication of severe calcium intoxication. Parathyroidectomy is the only curative method for hyperparathyroid crisis. Several case reports and case series have been published on the medical and surgical treatments for hyperparathyroid crisis, however, few reports have focused on the associated perioperative anesthetic management.
View Article and Find Full Text PDFIncreased Prevalence of Nephrolithiasis and Hyperoxaluria in Paget Disease of Bone.
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Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Context: Nephrolithiasis (NL) and primary hyperparathyroidism (HPTH) are metabolic complications of Paget disease of bone (PDB), but recent data regarding their prevalence in PDB patients are lacking.
Objectives: Study 1: To compare the prevalence of primary HPTH and NL in 708 patients with PDB and in 1803 controls. Study 2: To evaluate the prevalence of NL-metabolic risk factors in 97 patients with PDB and NL, 219 PDB patients without NL, 364 NL patients without PDB, and 219 controls, all of them without HPTH.
Brown tumor of the thoracic spine presenting with paraplegia in a patient with peritoneal dialysis.
CEN Case Rep
November 2019
Division of Nephrology, Department of Internal Medicine, Erciyes University Medical Faculty, 38039, Kayseri, Turkey.
Secondary and tertiary hyperparathyroidism is an important problem of chronic kidney disease. Brown tumor is a benign, unusual, reactive lesion as a result of disturbed bone remodeling, from long-standing increase in parathyroid hormone level. Brown tumors may cause morbidity due to pressure symptoms on neural structures and spontaneous bone fractures.
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