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A novel cryopreservation solution for adipose tissue based on metformin.
Stem Cell Res Ther
January 2025
Department of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi Guizhou, 563003, China.
Background: Autologous fat grafting (AFG) often needs multiple sessions due to low volume retention. Young adipose tissue demonstrates a more pronounced therapeutic effect; thus, the cryopreservation of adipose tissue of young origin is particularly crucial. This study investigated the protective effect of a new cryopreservation solution combining trehalose, glycerol, and metformin on adipose tissue.
View Article and Find Full Text PDFFacial Skin Quality Improvement After Treatment With CPM-HA20G: Clinical Experience in Korea.
J Cosmet Dermatol
January 2025
Human Dermatology Clinic, Incheon, Republic of Korea.
Background: Intradermal injection of CPM-HA20G, a low-viscoelasticity hyaluronic acid (HA) dermal filler with glycerol, has been shown to be effective for facial rejuvenation in Caucasians, but research in Asians is limited.
Aims: This study aimed to evaluate the effectiveness and safety of CPM-HA20G in enhancing facial skin quality in Korean women using a protocol developed by local aesthetic experts.
Patients/methods: In this 24-week prospective, single-arm, open-label study, 20 women received CPM-HA20G injections in the immediate subdermal layer on the anterior cheek (1 mL per side; total 2 mL) in three sessions every 4 weeks.
Optimization of canine sperm cryopreservation by focusing on glycerol concentration and freezing rate.
Vet Res Commun
January 2025
Faculty of Agriculture, University Farm, Utsunomiya University, Tochigi, 321-4415, Japan.
The purpose of this study was to improve the quality of frozen-thawed canine spermatozoa through the optimization of glycerol concentration (GC) and freezing rate in the semen freezing protocol. Ejaculates from nine dogs were diluted with an extender containing 0%, 1.5%, 3%, 6%, or 9% glycerol.
View Article and Find Full Text PDFGlycerol-3-Phosphate Dehydrogenase 1 Deficiency and Steatotic Liver Disease in Children: Our Cases and Review of Literature.
J Clin Exp Hepatol
December 2024
Departments of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Introduction: Glycerol-3-phosphate dehydrogenase 1 (GPD1) deficiency is an autosomal recessive disorder causing hypertriglyceridemia, hepatomegaly, fatty liver, and hepatic fibrosis in infancy. It is an under-recognized cause of pediatric steatotic liver disease (SLD) with only 36 cases reported worldwide.
Method: We analyzed the clinical profile of our five cases diagnosed by exome sequencing (ES) and reviewed the published cases till December 2023 using PubMed search.
Can switching stimulus polarity identify Meniere's disease? A preliminary investigation on ABR.
Acta Otolaryngol
January 2025
School of Audiology and Speech Language Pathology, Bharati Vidyapeeth (Deemed to be University), Pune, India.
Background: Meniere's disease (MD) affects 0.2% to 0.5% of the global population, with regional variations.
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