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Hybrid Hydrogel Supplemented with Algal Polysaccharide for Potential Use in Biomedical Applications.

Gels

December 2024

Department of Inorganic Chemistry, Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030016 Bucharest, Romania.

Hydrogels are a viable option for biomedical applications due to their biocompatibility, biodegradability, and ability to incorporate various healing agents while maintaining their biological efficacy. This study focused on the preparation and characterization of novel hybrid hydrogels enriched with the natural algae compound Ulvan for potential use in wound dressings. The characterization of the hydrogel membranes involved multiple methods to assess their structural, mechanical, and chemical properties, such as pH measurements, swelling, moisture content and uptake, gel fraction, hydrolytic degradation, protein adsorption and denaturation tests, rheological measurements, SEM, biocompatibility testing, and scratch wound assay.

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Cellulose nanocrystal-based synthetic biodegradable biopolymeric composites: A comprehensive review on recent progress.

Int J Biol Macromol

January 2025

Faculty of Chemical and Food Engineering, Bahir Dar Institute of Technology, Bahir Dar University, PO Box 26, Bahir Dar, Ethiopia; Faculty of Production and Power Engineering, University of Agriculture in Krakow, Balicka 116B, 30-149 Krakow, Poland.

With the worldwide transformation to a circular and low-carbon economy, the demand for sustainable materials has skyrocketed in recent years. Of various methods, sustainable and biodegradable biopolymers derived from renewable bioresources have received significant interest. Synthetic biodegradable biopolymers offer tremendous advantages over natural biodegradable biopolymers due to their stability, flexibility, and a wide range of achievable properties to fit several applications.

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Synthesis and characterization of photo-cross-linkable quince seed-based hydrogels for soft tissue engineering applications.

Carbohydr Polym

March 2025

Institute of Biomedical Engineering, Department of Pharmacology and Physiology, Faculty of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada; Azrieli Research Center, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC H3T 1C5, Canada; Montreal TransMedTech Institute, Montreal, QC H3T 1J4, Canada. Electronic address:

The convenience, versatility, and biocompatibility of photocrosslinkable hydrogel precursors make them promising candidates for developing tissue engineering scaffolds. However, the current library of photosensitive materials is limited. This study reports, for the first time, the modification of quince seed mucilage (QS) with glycidyl methacrylate (GM), resulting in the synthesis of methacrylated QS (QSGM).

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Background: Spinal cord injury (SCI) treatment remains a formidable challenge, as current therapeutic approaches provide only marginal relief and fail to reverse the underlying tissue damage. This study aims to develop a novel composite material combining enzymatic nanoparticles and nerve growth factor (NGF) to modulate the immune microenvironment and enhance SCI repair.

Methods: CeMn nanoparticles (NP) and CeMn NP-polyethylene glycol (PEG) nanozymes were synthesized via sol-gel reaction and DSPE-mPEG modification.

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In order to enhance the aging resistance, high temperature stability and low temperature crack resistance of asphalt pavement materials, 0.06% oxidized graphene (GO) and 12% polyurethane (PU) were used as composite modifiers to modify the base asphalt. The RTFOT test was conducted to evaluate the anti-aging performance of the modified asphalt.

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