We retrospectively reviewed the results in fourteen patients in whom salvage of an acutely infected total knee arthroplasty was attempted between 1970 and 1981 by the implantation of a new prosthesis within two weeks of removal of the infected one. Salvage was successful in six of the seven patients with a low-virulence infection but in only two of the seven patients with a high-virulence infection. Of the eight patients for whom the result was a functioning prosthesis, two had significant restriction of motion and one had moderate pain. If these three patients are eliminated from analysis, the over-all success rate is only 35 per cent (five of fourteen patients). We concluded that the implantation of another prosthesis for the treatment of infection of a total knee arthroplasty should be done with caution, and preferably when the infection has been caused by a low-grade organism and after a waiting period of longer than two weeks.
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