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Comparative study of the toxicity responses of Vallisneria natans and Pistia stratiotes to sulfadiazine under different planting methods.

J Hazard Mater

January 2025

Ministry of Ecology and Environment Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Polution, Chengdu University of Technology, Chengdu 610059, China. Electronic address:

Sulfonamides are receiving increased attention due to their persistence in the environment and potential ecological risks. However, there are currently relatively few studies on the toxicity response of aquatic plants grown under the single and mixed planting methods to sulfadiazine (SD). This study investigated the response of the Vallisneria natans (Lour.

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Response to azathioprine treatment in autoimmune hepatitis is dependent on glutathione transferase genotypes.

Dig Liver Dis

January 2025

Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden; Department of Laboratory Medicine, Region Jönköping County, Jönköping, Sweden. Electronic address:

Background: Azathioprine (AZA) is part of the standard treatment for autoimmune hepatitis (AIH). The first step in the complex bioconversion of AZA to active metabolites is mediated by glutathione transferases (GSTs).

Aims: Elucidate the association between GSTM1 and GSTT1 copy number variation (CNV), genetic variation in GSTA2, GSTP1, and inosine-triphosphate-pyrophosphatase, and the response to AZA in AIH.

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Bee population decline is associated with various stressors, including exposure to pollutants. Among these, titanium dioxide (TiO), an emerging nanoparticle (NP) pollutant, potentially affects living organisms, including bees. This study evaluates the impact of TiO NPs ingestion (1.

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24-epibrassinolide regulates oxytetracycline-induced phytotoxicity and its detoxification mechanism.

Ecotoxicol Environ Saf

January 2025

Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province, College of Biological and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, China. Electronic address:

Oxytetracycline (OTC), a crop-absorbable antibiotic, poses a health risk to humans through the food chain. Conversely, 24-epibrassinolide (EBL), a plant growth hormone, mitigates the toxic effects of various pollutants on plants. However, the mechanism by which exogenous EBL affects the growth of rape seedlings exposed to OTC remains largely unknown.

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HP1 Promotes the Centromeric Localization of ATRX and Protects Cohesion by Interfering Wapl Activity in Mitosis.

Front Biosci (Landmark Ed)

January 2025

The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Hunan Normal University Health Science Center, 410013 Changsha, Hunan, China.

Background: α thalassemia/mental retardation syndrome X-linked (ATRX) serves as a part of the sucrose nonfermenting 2 (SNF2) chromatin-remodeling complex. In interphase, ATRX localizes to pericentromeric heterochromatin, contributing to DNA double-strand break repair, DNA replication, and telomere maintenance. During mitosis, most ATRX proteins are removed from chromosomal arms, leaving a pool near the centromere region in mammalian cells, which is critical for accurate chromosome congression and sister chromatid cohesion protection.

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