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Specialization for different memory dimensions in brain activity evoked by cued recollection.

Neuroimage

January 2025

Department of Neuroscience, Imaging and Clinical Sciences, University G. d'Annunzio of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti, Italy; ITAB Institute for Advanced Biomedical Technologies, University G. d'Annunzio of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti, Italy. Electronic address:

Cued recollection involves the retrieval of different features of the encoded event. Previous research has shown that the recollection of complex events jointly recruits the Default Mode and the Frontoparietal Control networks, but the degree to which activity within these networks varies as a function of the particular memory dimension (e.g.

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Background: The tooth exhibits increased sensitivity to noxious stimuli due to the dense innervation of thin myelinated Aδ fibers and unmyelinated C fibers within the dental pulp. While prior research has identified dynorphin expression in layers I-II of the dorsal horn across the spinal cord in various pain models, its functional role in trigeminal nociception, including tooth pain, remains underexplored. This study examines the potential role of dynorphin in the nociceptive processing of dental stimuli.

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Introduction: Threats to our survival are often posed by the environment in which humans have evolved or live today. Animal and human ancestors developed complex physiological and behavioral response systems to cope with two types of threats: immediate physical harm from predators or conspecifics, triggering fear, and the risk of infections from parasites and pathogens leading to the evolution of the behavioral immune system (BIS) with disgust as the key emotion. Here we ask whether the BIS has adapted to protect us from pandemic risks or poisoning by modern toxic substances.

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MuSK regulates neuromuscular junction Nav1.4 localization and excitability.

J Neurosci

January 2025

Carney Institute for Brain Science, Brown University, Providence, RI 02912

The neuromuscular junction (NMJ) is the linchpin of nerve-evoked muscle contraction. Broadly, the function of the NMJ is to transduce nerve action potentials into muscle fiber action potentials (MFAPs). Efficient neuromuscular transmission requires both cholinergic signaling, responsible for generation of endplate potentials (EPPs), and excitation, the amplification of the EPP by postsynaptic voltage-gated sodium channels (Nav1.

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Historically, the film industry has been male-dominated both in front of and behind the camera, resulting in a longstanding gender imbalance in storytelling and representation. This legacy of male-centric narratives may unconsciously influence critics' expectations and judgments. Existing literature suggests that negative critiques in movie reviews can significantly impact actors' earnings by diminishing a film's commercial prospects.

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