Peripheral blood lymphocytes of hospital personnel handling cytostatic drugs showed no elevation of structural chromosomal aberrations or sister-chromatid exchanges (SCE) over the baseline. The urine of the probands did not induce SCE in peripheral lymphocytes in vitro.
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http://dx.doi.org/10.1016/0165-7992(83)90211-7 | DOI Listing |
Semergen
November 2024
Coordinadora de Enfermería, Centro de Salud Almoradí, Departamento de Salud de Orihuela, Almoradí, Alicante, España.
Objective: To know the perception of nurses about the management and exposure of methotrexate in primary care nursing staff of the Orihuela Health Department.
Material And Method: This is a descriptive qualitative study carried out through semi-structured interviews with a sample of 15 intentionally selected nurses.
Results: The participants expressed concern about the handling and exposure of methotrexate, which allowed them to perceive training as the greatest concern in the study unit.
Front Public Health
September 2023
National School of Occupational Medicine, Carlos III Health Institute, Madrid, Spain.
Background: This review wants to highlight the importance of computer programs used to control the steps in the management of dangerous drugs. It must be taken into account that there are phases in the process of handling dangerous medicines in pharmacy services that pose a risk to the healthcare personnel who handle them. Objective: To review the scientific literature to determine what computer programs have been used in the field of hospital pharmacy for the management of dangerous drugs (HDs).
View Article and Find Full Text PDFAllergol Select
August 2023
Allergology and Immunology, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Not available.
View Article and Find Full Text PDFMed Pr
December 2022
University of Florence, Florence, Italy (Department of Experimental and Clinical Medicine).
Background: Chemotherapy drugs are widely used to treat cancer, but their active compounds represent a danger for workers who could be exposed to them. However, they aren't yet included in directive CE No. 1272/2008 and the European Biosafety Network has only recommended a limit value of 100 pg/cm for surface contamination.
View Article and Find Full Text PDFJ Anal Toxicol
January 2023
Toxicology Service, Institute of Forensic Sciences, University of Santiago de Compostela, Santiago de Compostela, Spain.
The ever-increased usage of cytostatic drugs leads to high risk of exposure among healthcare workers. Moreover, workers are exposed to multiple compounds throughout their lives, leading to cumulative and chronic exposure. Therefore, multianalyte methods are the most suitable for exposure assessment, which minimizes the risks from handling cytostatic drugs and ensures adequate contamination containment.
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