AI Article Synopsis

  • Anti-a2 sera from a3 rabbits identify unique determinants on a2 molecules that differ from those detected by anti-a2 sera from a1 rabbits.
  • These unique determinants can sometimes be found in a1 rabbits at low levels and are prevalent in various Leporidae species.
  • Both types of anti-a2 sera compete for the same binding site on a2 molecules, and all tested homogeneous a2 molecules display both determinant types.

Article Abstract

Anti-a2 sera raised in a3 rabbits are shown to detect determinants on a2 molecules which are different from those detected by anti-a2 sera raised in a1 animals. The former determinants are occasionally observed at a low level in rabbits of the a1 allotype and at a high level in sera of Leporidae of different genera. The two types of anti-a2 sera are shown to compete for the same sterical region of the a2 molecules. All homogeneous a2 molecules which have been tested show both types of determinants.

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http://dx.doi.org/10.1002/eji.1830070105DOI Listing

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