Three modified replications (N = 32, 46, and 32) investigated verbal and nonverbal interactions during role playing of family conflict by family groups of father, mother, and one child. Half the fathers had essential hypertension and half were normotensive. Nonverbal but not verbal behavior differed between families with hypertensive vs. normotensive fathers. Hypertensive fathers and their normotensive wives and children looked at each other less (gaze aversion), both while listening and speaking, than did the members of normotensive families. The difference in duration of gaze aversion occurred more prominently during emotionally negative verbalizations. The results suggest a pattern of conflict avoidance in families with a hypertensive father.
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http://dx.doi.org/10.1097/00006842-198306000-00006 | DOI Listing |
Sleep Breath
January 2025
Clinical Internal Medicine Department, Shanghai Health and Medical Center, Wuxi, 214065, People's Republic of China.
Background: Obstructive sleep apnea has been associated with various urinary system diseases, including prostatic hyperplasia and nocturia. Recently, it has been linked to prostate cancer. This study investigated the relationship between the apnea hypopnea index, prostate-specific antigen (PSA) levels, and changes in PSA.
View Article and Find Full Text PDFGeroscience
January 2025
Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 02111, USA.
Using whole-genome sequencing (WGS) might offer insights into rare genetic variants associated with healthy aging and extreme longevity (EL), potentially pointing to useful therapeutic targets. In this study, we conducted a genome-wide association study using WGS data from the Long Life Family Study and identified a novel longevity-associated variant rs6543176 in the SLC9A2 gene. This SNP also showed a significant association with reduced hypertension risk and an increased, though not statistically significant, cancer risk.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Brain and Mind Institute, Aga Khan University, Nairobi, Kenya.
Background: Alzheimer's disease (AD) is the most common type of dementia globally and is the fifth leading cause of death and disability. About half of all people suffering from the disease are living in sub-Saharan African Countries including Kenya. However, research on dementia has been almost exclusively focused on the Global North societies.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Departments of Psychiatry and Behavioral Sciences, Neurology, and Epidemiology, University of California San Francisco, San Francisco, CA, USA.
Background: Integrating clinical and genetic risk factors for dementia in a precision medicine framework can play a crucial role in primary prevention. Here, we ascertained the proportion of individuals who are at heightened risk of developing dementia based on their family history, genetic, and clinical risk factors and evaluated how the additive burden of these risk indicators is associated with incident dementia.
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Alzheimers Dement
December 2024
Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
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