The first two cases of human ophthalmic infections due to Streptococcus equisimilis (group C) are reported. This organism is known to produce severe infections in animals, but infection in humans is rare. The distinction between beta-hemolytic group C streptococci and group A and their ability to cause disease in susceptible patients is discussed.
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http://dx.doi.org/10.1093/ajcp/79.3.385 | DOI Listing |
Iran J Microbiol
October 2024
Department of Microbiology, Mallareddy Medical College for Women, Hyderabad, India.
Background And Objectives: Leprosy foot ulcers (LFU) tend to become chronic due to secondary bacterial infections, leading to subsequent disfigurement and disability. Treatment modality for infected plantar ulcers thus so far is majorly based on conventional approach of empirical antibacterial therapy. However, this approach tends to overlook unconventional pathogens which are likely to be present in the LFU.
View Article and Find Full Text PDFmBio
November 2024
Laboratory for Molecular and Translational Human Infectious Diseases Research, Center for Infectious Diseases, Houston Methodist Research Institute, Houston, Texas, USA.
Unlabelled: subspecies (SDSE) is a Gram-positive bacterial pathogen that infects humans and is closely related to group A streptococcus (GAS). Compared with GAS, far less is known about SDSE pathobiology. Increased rates of invasive SDSE infections have recently been reported in many countries.
View Article and Find Full Text PDFIndian J Med Microbiol
December 2024
Department of Clinical Microbiology, Christian Medical College, Vellore, India. Electronic address:
Background: Streptococcus dysgalactiae subsp equisimilis (SDSE) is an emerging pathogen causing pharyngitis and post-streptococcal sequelae like S. pyogenes. SDSE was initially considered a commensal microorganism inhabiting the upper respiratory tract and skin.
View Article and Find Full Text PDFBMC Microbiol
September 2024
Department of Molecular Genetics and Infection Biology, University of Greifswald, Greifswald, Germany.
Background: Streptococcus dysgalactiae subspecies equisimilis (SDSE) is increasingly recognized as an emerging cause of invasive diseases including necrotizing soft tissue infections (NSTIs). In contrast to the closely related Streptococcus pyogenes, SDSE infections mainly affect older and comorbid patients. Biofilm formation has been demonstrated in soft tissue biopsies of S.
View Article and Find Full Text PDFArch Biochem Biophys
November 2024
Key Lab of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing, 100084, China. Electronic address:
Hyaluronic acid (HA) is a glycosaminoglycan essential for cellular processes and finding increasingly applications in medicine, pharmaceuticals, and cosmetics. While membrane-integrated Class I hyaluronan synthase (HAS) catalyzes HA synthesis in most organisms, the molecular mechanisms by which HAS-lipid interactions impact HAS catalysis remain unclear. This study employed coarse-grained molecular dynamics simulation combined with dimensionality reduction to uncover the interplay between lipids and Streptococcus equisimilis HAS (SeHAS).
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