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Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation.
Invest Ophthalmol Vis Sci
January 2025
Vitreous Retina Macula Consultants of New York, New York, United States.
Purpose: The purpose of this study was to develop ground-truth histology about contributors to variable fundus autofluorescence (FAF) signal and thus inform patient selection for treating geographic atrophy (GA) in age-related macular degeneration (AMD).
Methods: One woman with bilateral multifocal GA, foveal sparing, and thick choroids underwent 535 to 580 nm excitation FAF in 6 clinic visits (11 to 6 years before death). The left eye was preserved 5 hours after death.
Categorization processes in emotion expression recognition: The roles of language and essentialism.
Emotion
January 2025
Department of Psychology, University of New Hampshire.
We examined categorical processing biases in the perception and recognition of facial expressions of emotion across two studies. In both studies, participants first learned to discriminate between two ambiguous facial expressions of emotion selected from the middle of a continuous array of blended expressions (i.e.
View Article and Find Full Text PDFImproving estimation efficiency for survival data analysis by integrating a coarsened time-to-event outcome from an external study.
Biometrics
January 2025
Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, United States.
In the era of big data, increasing availability of data makes combining different data sources to obtain more accurate estimations a popular topic. However, the development of data integration is often hindered by the heterogeneity in data forms across studies. In this paper, we focus on a case in survival analysis where we have primary study data with a continuous time-to-event outcome and complete covariate measurements, while the data from an external study contain an outcome observed at regular intervals, and only a subset of covariates is measured.
View Article and Find Full Text PDFEducation Research: Making a Tweetorial Fly: Features of Educational Social Media Posts Associated With High Sharing and Engagement.
Neurol Educ
December 2024
From the Departments of Neurology and Neurosurgery (C.S.W.A., E.C.L.), Emory University School of Medicine, Atlanta, GA; Division of Biostatistics (T.M.), Rollins School of Public Health, Emory University, Atlanta, GA; Department of Neurology (G.F.P.), University of Pittsburgh, PA; Department of Neurology (A.S.Z.), Weill Cornell Medical College, New York, NY; Emory University School of Medicine (N.D.), Atlanta, GA; Consulting Web Developer (S.M.), Scotland; Department of Neurology (A.S.), Wake Forest University, Winston-Salem, NC; Departments of Neurology and Neurosurgery (N.S.D), Icahn School of Medicine at Mount Sinai, New York, NY; Department of Neurology (A.L.B.), University of California, San Francisco; Department of Neurology (N.A.M.), University of Maryland School of Medicine, Baltimore, MD; and Department of Neurology (L.K.J.), Mayo Clinic, Rochester, MN.
Background And Objectives: Social media platforms such as X (formerly Twitter) are increasingly used in medical education. Characteristics of tweetorials (threaded teaching posts) associated with higher degrees of engagement are unknown. We sought to understand features of neurology-themed tweetorials associated with high sharing and engagement.
View Article and Find Full Text PDFBranched-Chain Amino Acid Supplements for Sarcopenia in Liver Cirrhosis: A Systematic Review and Meta-analysis.
J Clin Exp Hepatol
September 2024
Department of Gastroenterology and hepatology, Baylor College of Medicine, Houston, TX, USA.
Background: Sarcopenia, a key aspect of malnutrition in liver cirrhosis (LC), affects 30-70% of LC patients. Given the inconsistent results from RCTs on branched-chain amino acids (BCAAs) for treating sarcopenia in LC, we conducted a systematic review and meta-analysis to assess the efficacy and safety of BCAAs for sarcopenia management in LC patients.
Methods: A systematic review and meta-analysis synthesizing evidence from RCTs obtained from PubMed, Embase, Cochrane, Scopus, and Web of Science from inception to April 2024.
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