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A 39-year-old man presented with priapism. To facilitate corporal cavernosal aspiration, a dorsal penile nerve block was performed. A dose of 2000mg lignocaine was administered, instead of the intended 200mg.

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Sickle cell anemia (SCA) is a monogenic blood disease with complex and multifactorial pathophysiology. The endocannabinoid system (ECS) could be a candidate for modulating SCA complications, such as priapism, as it has demonstrated an essential role in hematopoiesis, platelet aggregation, and immune responses. We evaluated the association of ECS-related single nucleotide polymorphisms (SNP) (FAAH rs324420, MAGL rs604300, CNR1 rs7766029, and CNR2 rs35761398) with priapism in a Brazilian SCA cohort.

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Article Synopsis
  • The study aimed to analyze pre- and intraoperative factors influencing the integrity of corporal bodies after placing an inflatable penile prosthesis (IPP), focusing on the occurrence of intraoperative and postoperative complications.
  • Researchers reviewed a database of over 5,400 IPP surgeries conducted between 2016 and 2021, identifying significant predictors for complications linked to corporal integrity.
  • Key predictors for complications included revision surgery, older age, and medical conditions like coronary artery disease or peripheral vascular disease, indicating the need for consideration of these factors during IPP placement to reduce risks.
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The assessment and aetiology of drug-induced ischaemic priapism.

Int J Impot Res

December 2024

Associate Professor in the Division of Urology, Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Ischaemic priapism is a urological emergency characterised by a prolonged, painful erection unrelated to sexual stimulation. While several aetiological factors contribute to this condition, the pharmacological causes have gained significant attention in recent years. This narrative review aims to comprehensively assess ischaemic priapism, specifically focusing on its pharmacological aetiology.

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Outcomes of scrotal urethrostomy with poliglecaprone 25 in dogs: 67 cases (2011 to 2023).

Can Vet J

December 2024

Garden State Veterinary Specialists, 246 Industrial Way West, Eatontown, New Jersey 07724, USA.

Objective: To determine the complication rate of canine scrotal urethrostomy (SU) performed with poliglecaprone 25 and identify risk factors for complications.

Animals: We studied 67 dogs treated with SU.

Procedure: Medical records of dogs that underwent SU between 2011 and 2023 at Garden State Veterinary Specialists and its satellite hospitals were reviewed.

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