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Regular Smoking Accelerates the Decline in Masticatory Performance in Japanese Men: The Suita Study.
J Oral Rehabil
January 2025
Department of Removable Prosthodontics and Gerodontology, Osaka University Graduate School of Dentistry, Suita, Japan.
Background: Smoking is presumed to cause a decline in masticatory performance by worsening the intraoral environment in various ways. However, no longitudinal study has examined the relationship between smoking and masticatory performance.
Objectives: To clarify how smoking affects future decline in masticatory performance through a 5-year follow-up study of a general urban population.
R21 in Matrix-M adjuvant in UK malaria-naive adult men and non-pregnant women aged 18-45 years: an open-label, partially blinded, phase 1-2a controlled human malaria infection study.
Lancet Microbe
January 2025
Jenner Institute, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.
Background: R21 is a novel malaria vaccine, composed of a fusion protein of the malaria circumsporozoite protein and hepatitis B surface antigen. Following favourable safety and immunogenicity in a phase 1 study, we aimed to assess the efficacy of R21 administered with Matrix-M (R21/MM) against clinical malaria in adults from the UK who were malaria naive in a controlled human malaria infection study.
Methods: In this open-label, partially blinded, phase 1-2A controlled human malaria infection study undertaken in Oxford, Southampton, and London, UK, we tested five novel vaccination regimens of R21/MM.
Management of a Muskellunge Fish Bite to the Thumb With Subsequent Flexor Tendon Laceration.
Cureus
December 2024
Plastic Surgery, West Virginia University School of Medicine, Morgantown, USA.
Despite frequent occurrences, especially throughout the Appalachian region, fish bite injuries remain largely underreported. Muskellunge anglers are at a particularly heightened risk due to the fish's large mouth and notably sharp teeth. We present a case of a male who sustained an injury to the right volar thumb following a muskellunge bite.
View Article and Find Full Text PDFBiomechanics of severe open-bite treatment with temporary anchorage devices.
J Clin Orthod
November 2024
Division of Orthodontics, Department of Craniofacial Sciences; Division of Orthodontics, University of Connecticut School of Dental Medicine, Farmington, CT.
Sporotrichoid Nocardiosis in an Immunocompetent Patient: A Case Report.
Cureus
December 2024
Internal Medicine, AdventHealth Orlando, Orlando, USA.
spp. rarely cause infection in humans and are most common in the immunocompromised population. Pulmonary nocardiosis is the most common presentation.
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