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Effects of D-Tagatose on Cariogenic Risk: A Systematic Review of Randomized Clinical Trials.
Nutrients
January 2025
Escuela de Kinesiología, Facultad de Salud, Universidad Santo Tomás, Talca 3460000, Chile.
Unlabelled: Dental caries remains a prevalent chronic disease driven by dysbiosis in the oral biofilm, with playing a central role in its pathogenesis.
Objective: This study aimed to assess the effect of D-tagatose on cariogenic risk by analyzing randomized clinical trials (RCTs).
Methods: A systematic literature review was conducted targeting RCTs published up to 2024 in eight databases and two gray literature sources.
Sulforaphane as a promising anti-caries agents: inhibitory effects on and caries control in a rat model.
Front Microbiol
January 2025
State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Dental caries has been one of the most prevalent diseases globally over the last few decades, threatening human oral and general health. The most critical aspect in caries control is to inhibit the dominant cariogenic bacteria (). Sulforaphane (SFN), a compound found in a wide range of cruciferous plants, has demonstrated bacteriostatic activities against various pathogenic bacteria.
View Article and Find Full Text PDFLayer-by-layer coated probiotics with tannic acid-Ca and casein phosphopeptide complexes for caries prevention and enamel remineralization.
iScience
January 2025
Department of Orthodontics, Tianjin Medical University School and Hospital of Stomatology & Tianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, No.12 Qixiangtai Road, Heping District, Tianjin 300070, P.R. China.
Dental caries is a common disease resulting from tooth demineralization caused by bacterial plaque. Probiotics have shown great potential against caries by regulating the balance of oral flora. However, obstacles such as poor colonization and lysozyme sensitivity in oral cavity hinder their further application.
View Article and Find Full Text PDFComparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro study.
Sci Rep
January 2025
Conservative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
The main objective of the current study is to compare short-term fluoride release of three ion releasing restorative materials and assess their inhibitory effect on secondary caries. Materials used in this study included, Self-adhesive hybrid composite (group A), Ion releasing flowable composite liner (group B), and alkasite restorative material (group C). Twenty-two discs were fabricated from each material for short-term fluoride release test, conducted on days 1, 7, and 14.
View Article and Find Full Text PDFA Pyrroloquinazoline Analogue Regulated Streptococcus mutans and Streptococcus sanguinis Dual-Species Biofilms.
Int Dent J
January 2025
School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, China; Department of Endodontics, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, China. Electronic address:
Objective: Selective inhibition of cariogenic bacteria is regarded as a potential strategy against caries. To assess the potential of SCH-79797, one novel promising antibiotic, in microbial equilibrium using a dual-species biofilms model of Streptococcus mutans (S. mutans) and Streptococcus sanguinis (S.
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