Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Limiting cap-dependent translation increases 20S proteasomal degradation and protects the proteomic integrity in autophagy-deficient skeletal muscle.
Autophagy
January 2025
Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Postmitotic skeletal muscle critically depends on tightly regulated protein degradation to maintain proteomic stability. Impaired macroautophagy/autophagy-lysosomal or ubiquitin-proteasomal protein degradation causes the accumulation of damaged proteins, ultimately accelerating muscle dysfunction with age. While studies have demonstrated the complementary nature of these systems, their interplay at the organism levels remains poorly understood.
View Article and Find Full Text PDFDistribution of Tunisian beet wild relatives ( sp.) according to morphological characteristics and eco-geographical origin.
Heliyon
January 2025
Laboratory of Plant Protection, National Institute of Agronomic Research of Tunisia, University of Carthage, Rue Hedi Karray, 2049, El-Menzah, Tunisia.
subsp. (L.) Arcang.
View Article and Find Full Text PDFPhoton-counting computed tomography (PCCT) is superior in providing better CT image contrast than traditional CT technology. However, noticeable ring artifacts are more likely caused by the imperfect functioning of photon-counting detectors. This study proposes an efficient ring artifacts correction approach based on the unique characteristics of unwanted components in multi-domains.
View Article and Find Full Text PDFT cell immune evasion by SARS-CoV-2 JN.1 escapees targeting two cytotoxic T cell epitope hotspots.
Nat Immunol
January 2025
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Although antibody escape is observed in emerging severe acute respiratory syndrome coronavirus 2 variants, T cell escape, especially after the global circulation of BA.2.86/JN.
View Article and Find Full Text PDFThe meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis.
Sci Immunol
January 2025
Department of Immunology, Harvard Medical School; Boston, MA, USA.
Our understanding of the meningeal immune system has recently burgeoned, particularly regarding how innate and adaptive effector cells are mobilized to meet brain challenges. However, information on how meningeal immunocytes guard brain homeostasis in healthy individuals remains limited. This study highlights the heterogeneous, polyfunctional regulatory T cell (T) compartment in the meninges.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!