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Preliminary observations in cortical excitability changes using transcranial magnetic stimulation (TMS), it's correlation with diffusion tensor imaging (DTI) in subjects with neuromyelitis optica spectrum disorder (NMOSD).
Acta Neurol Belg
January 2025
Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, 560029, India.
Background: Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing central nervous system disease most commonly associated with aquaporin-4 antibodies (AQP4-Ab) and Myelin oligodendrocyte glycoprotein (MOG) antibodies. These demyelinating disorders influence cortical excitability, which has been studied using advanced imaging techniques and transcranial magnetic stimulation (TMS) in our study.
Methods: This is a prospective study of 30 subjects.
Risk Communication and Community Engagement (RCCE) implementations to control cholera outbreak in Oromia region, Ethiopia.
Trop Med Health
January 2025
School of Medical Laboratory Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.
Background: Oromia regional state experiencing cholera outbreaks in a protracted pattern despite various interventions at local and regional levels. This study aimed to examine the implementation of Risk Communication and Community Engagement (RCCE) activities for cholera outbreak control in the region.
Methods: We conducted a quantitative and qualitative mixed-method study.
Neighborhood environment associations with cognitive function and structural brain measures in older African Americans.
BMC Med
January 2025
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Background: Since older adults spend significant time in their neighborhood environment, environmental factors such as neighborhood socioeconomic disadvantage, high racial segregation, low healthy food availability, low access to recreation, and minimal social engagement may have adverse effects on cognitive function and increase susceptibility to dementia. DNA methylation, which is associated with neighborhood characteristics as well as cognitive function and white matter hyperintensity (WMH), may act as a mediator between neighborhood characteristics and neurocognitive outcomes.
Methods: In this study, we examined whether DNA methylation in peripheral blood leukocytes mediates the relationship between neighborhood characteristics and cognitive function (N = 542) or WMH (N = 466) in older African American (AA) participants without preliminary evidence of dementia from the Genetic Epidemiology Network of Arteriopathy (GENOA).
Objectives: To assess the diagnostic rates of forensic case patients who sought gynecological and obstetrics care, as well as the differences in forensic report production based on the event.
Study Design: The following factors were looked into: age of the patients, time between the incident and consultation, reason for consultation (pregnancy determination during the post-divorce waiting period, sexual assault, hymen examination, physical violence, other), time of the consultation (in-hours or out-of-hours), place of referral (prosecutor's office/court, police station, own request), and type of report (final or preliminary). The data were obtained retrospectively.
Land-derived metals impact the survival and settlement of larval mussels.
Environ Pollut
January 2025
Cawthron Institute, 98 Halifax Street East, Nelson, 7010, New Zealand.
Global declines in wild mussel populations and production have been linked to the impacts of climate change and pollution. Summer die-offs of mussels (Perna canaliculus), spat retention issues, and a severe decline in mussel spat settlement have been reported in the Marlborough Sounds, an important area for mussel farming in New Zealand. Preliminary evidence suggests that naturally occurring contaminants and changing land use in the surrounding areas, could contribute to the decline of this species.
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