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Metamorphic Proteins to Achieve Conformationally Selective Material Surface Binding.
Small
January 2025
Department of Chemistry, University of Miami, Coral Gables, FL, 33146, USA.
The controlled binding of proteins on nanoparticle surfaces remains a grand challenge required for many applications ranging from biomedical to energy storage. The difficulty in achieving this ability arises from the different functional groups of the biomolecule that can adsorb on the nanoparticle surface. While most proteins can only adopt a single structure, metamorphic proteins can access at least two different conformations, which presents intriguing opportunities to exploit such structural variations for binding to nanoparticles.
View Article and Find Full Text PDFRoom-Temperature Magnetic Antiskyrmions in Canted Ferrimagnetic CoHo Alloy Films.
Adv Mater
January 2025
School of Materials Science and Engineering, Key Laboratory of Advanced Materials and Devices for Post-Moore Chips, Ministry of Education, University of Science and Technology Beijing, Beijing, 100083, China.
Magnetic antiskyrmions, the anti-quasiparticles of magnetic skyrmions, possess alternating Bloch- and Néel-type spin spirals, rendering them promising for advanced spintronics-based information storage. To date, antiskyrmions are demonstrated in a few bulk materials featuring anisotropic Dzyaloshinskii-Moriya interactions and a limited number of artificial multilayers. Identifying novel film materials capable of hosting isolated antiskyrmions is critical for memory applications in topological spintronics.
View Article and Find Full Text PDFReward and Efficacy Modulate the Rate of Anticipatory Pupil Dilation.
Psychophysiology
January 2025
Department of Experimental Psychology, Ghent University, Ghent, Belgium.
Pupil size is a well-established marker of cognitive effort, with greater efforts leading to larger pupils. This is particularly true for pupil size during task performance, whereas findings on anticipatory effort triggered by a cue stimulus are less consistent. For example, a recent report by Frömer et al.
View Article and Find Full Text PDFImpact of a very low-calorie ketogenic diet on metabolic and microbiota outcomes in post-bariatric patients and bariatric-Naïve individuals: A comparative pilot study.
Diabetes Obes Metab
January 2025
Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University, Rome, Italy.
Aims: To date, bariatric surgery (BS) is the most effective long-term treatment for obesity, but weight regain (WR) is common. The very low-calorie ketogenic diet (VLCKD) is effective for weight loss and may influence gut microbiota (GM) composition, but it has been scarcely evaluated in post-bariatric patients. This study compared the efficacy and safety of a VLCKD in patients with WR post-bariatric surgery (BS+) and in bariatric surgery-naïve patients (BS-).
View Article and Find Full Text PDFDistinct morphological drivers of jumping and maneuvering performance in gerbils.
J Exp Biol
January 2025
Department of Ecology, Evolution, and Organismal Biology, Brown University, Providence, RI, USA.
Theoretically, animals with longer hindlimbs are better jumpers, while those with shorter hindlimbs are better maneuverers. Yet experimental evidence of this relationship in mammals is lacking. We compared jump force and maneuverability in a lab population of Mongolian gerbils (Meriones unguiculatus).
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