AI Article Synopsis
- The study reviews four cases of Paget's deforming dystrophy affecting the jaw, noting that three were limited to the jawbone while one also impacted the skull and cranial nerves.
- It highlights a higher prevalence in females and involvement of the maxilla, with only one case affecting the mandible.
- The biochemical findings were consistent across all cases, mirroring those seen in more widespread Paget's disease, suggesting treatment options including medication and surgery when necessary for bone remodeling.
Article Abstract
This study describes four cases of Paget's deforming dystrophy involving the jaw. In three of them the course of the disease affected only the bone involved whilst in the fourth the bones of the vault of the skull and some cranial nerves were affected in time. The prevalence of the female sex and of involvement of the maxilla was evident. The mandible was involved in only one case. Biochemical abnormalities were the same in all cases as well as being identical to those in cases of Paget's disease with multiple bone involvement. The authors suggest medical treatment (calcitonin, Na etidronate, mitramycin ) and surgery only when required for bone remodelling when there is interference with function.
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