The degree and distribution of tooth decay in a group of juvenile periodontitis ( JP ) patients were compared with tooth decay in an age- and sex-matched periodontally normal control group. The experimental group was comprised of 13 patients of no more than 20 years of age who were designated as localized juvenile periodontitis patients ( LJP ) according to the definition of Baer, and 10 patients of no more than 25 years of age who were designated as generalized juvenile periodontitis patients ( GJP ), as described by Manson and Lehner . Twenty-three age- and sex-matched patients with no periodontal disease served as the control group. Caries was evaluated by standard clinical and radiographic criteria and quantitated by decayed, missing, filled teeth and surfaces (DMFS). Decay was further categorized as active proximal decay and as total proximal decay, which included both active proximal caries and restored proximal surfaces. A Student's t test revealed no statistical differences between the LJP and GJP groups. Moreover, there was no difference in the number of missing or filled teeth in the JP group as compared to the control group. However, 17 of the 23 JP patients had no proximal decay, whereas all but two of the 23 control patients had some proximal decay. Moreover, in the JP group ( LJP and GJP ) the mean values for active proximal decay and total proximal decay were both significantly lower than those in the control group (P less than 0.001). Thus, a low number of proximal carious lesions were found in the presence of juvenile periodontitis.(ABSTRACT TRUNCATED AT 250 WORDS)
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http://dx.doi.org/10.1902/jop.1984.55.4.242 | DOI Listing |
Nat Commun
January 2025
Institute of Flexible Electronics (IFE), Northwestern Polytechnical University, Xi'an, China.
Anion exchange membrane fuel cells (AEMFCs) are one of the ideal energy conversion devices. However, platinum (Pt), as the benchmark catalyst for the hydrogen oxidation reaction (HOR) of AEMFCs anodes, still faces issues of insufficient performance and susceptibility to CO poisoning. Here, we report the Joule heating-assisted synthesis of a small sized RuPt single-atom alloy catalyst loaded on nitrogen-doped carbon modified with single W atoms (s-RuPt@W/NC), in which the near-range single Ru atoms on the RuPt nanoparticles and the long-range single W atoms on the support simultaneously modulate the electronic structure of the active Pt-site, enhancing alkaline HOR performance of s-RuPt@W/NC.
View Article and Find Full Text PDFInt J Clin Pediatr Dent
November 2024
Department of Public Health Dentistry, Dr D Y Patil Dental College and Hospital, Dr D Y Patil Vidyapeeth, Pune, Maharashtra, India.
Introduction: Utilizing 38% silver diamine fluoride (SDF) has been demonstrated in clinical trials to prevent and halt early childhood caries (ECC). Based on a research evaluation, it has been found that 38% SDF can effectively prevent new tooth decay and stop existing tooth decay in children's primary teeth.
Objective: This study aimed to assess the survival of teeth treated with repeated applications of 38% SDF in children with ECC and to compare the outcomes between single and multiple applications.
Cell Res
January 2025
National Key Laboratory of Immunity & Inflammation, Second Military Medical University, Shanghai, China.
Immunometabolism is critical in the regulation of immunity and inflammation; however, the mechanism of preventing aberrant activation-induced immunopathology remains largely unclear. Here, we report that glyoxalase II (GLO2) in the glycolysis branching pathway is specifically downregulated by NF-κB signaling during innate immune activation via tristetraprolin (TTP)-mediated mRNA decay. As a result, its substrate S-D-lactoylglutathione (SLG) accumulates in the cytosol and directly induces D-lactyllysine modification of proteins.
View Article and Find Full Text PDFNeurol Ther
December 2024
Department of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui, China.
Objective: Aim: Assessment of dental caries and its impact on the level of dental health of children aged 15-18 years of Upper Tysa region, who constantly live in conditions of combined negative effects of factors of natural and technological genesis.
Patients And Methods: Materials and Methods: During the dental examination, the incidence of dental caries in 360 children aged 15-18 years from various biogeochemical zones of the cross-border region of the Upper Tysa region was studied and assessed using the International Caries Detection and Assessment System - ICDAS II (International Caries Detection and Assessment System).
Results: Results: It was found that the use of physiologically suboptimal drinking water from decentralized water resources is among the environmental determinants of the state of dental health of children in the Upper Potyssia.
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