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Treatment of idiopathic granulomatous mastitis: a retrospective case series.

Rheumatol Int

January 2025

Division of Rheumatology, Centre hospitalier de l'Université de Montréal (CHUM), Department of Medicine, Université de Montréal, Montreal, Canada.

Idiopathic granulomatous mastitis (IGM) is a rare inflammatory disease of the breast. Various clinical management approaches have been described, but their efficacy and optimal sequential order remain uncertain. We describe the first Canadian cohort of patients with IGM, discuss treatment outcomes and outline a practical management approach.

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We report a cluster of infections with genetically related toxigenic Corynebacterium diphtheriae linked to an outbreak among asylum seekers in Switzerland that subsequently affected patients without known exposure. This discovery highlights the importance of rapid, interdisciplinary outbreak investigations and regular vaccination status assessment, especially in elderly populations with waning immunity.

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Gas Chromatography-mass Spectrometry analysis, Biotoxicity and Antibiofilm Activities of Syzygium aromaticum against Corynebacterium diphtheriae.

An Acad Bras Cienc

December 2024

Universidade CEUMA, Laboratório de Cências Biomédicas, Rua Josué Montello, 1, Renascença II, 65075-120 São Luís, MA, Brazil.

The objective of this study was to investigate the chemical composition of Syzygium aromaticum essential oil (SAEO), both as its toxicity and biological activities on Corynebacterium diphtheriae. The essential oil (EO) was obtained by hydrodistillation and verified by GC-MS. The main chemical components were eugenol (48.

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An ultrasonic degraded polysaccharide extracted from Pueraria lobata ameliorate ischemic brain injury in mice by regulating the gut microbiota and LPS-TLR4 pathway.

Ultrason Sonochem

January 2025

Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. Electronic address:

Ischemia brain injury is closely associated with the gut microbiota. Polysaccharides, as a typical prebiotic, have been extensively employed in stroke treatment. In our previous study, Pueraria lobata polysaccharide (PLP-3) with antioxidant activity was prepared via water extraction and alcohol precipitation combined with ultrasonic degradation.

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Article Synopsis
  • * A case study involved a 44-year-old woman with a painful breast mass, ultrasound showed lesions and abscess formation, leading to a biopsy that confirmed inflammatory changes without cancer.
  • * The patient was treated with steroids and antibiotics, underwent surgery, and improved clinically, highlighting the need for better understanding of this condition and its optimal treatment options.
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