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Highly Efficient Dual-Probe Strategy toward Single-Cell Metabolite Analysis.
Anal Chem
January 2025
School of Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, Nantong 226019, P. R. China.
As cancer progresses, detached cancer cells metastasize through the circulatory system, followed by intricate metabolic rewiring for adaptation and propagation. The dynamic process of metastasis, despite being responsible for the majority of cancer-related deaths, still remains inadequately comprehended. Here, we proposed a microfluidic platform combining the dual-probe strategy for the detection of metastasize-related metabolic levels at single-cell resolution.
View Article and Find Full Text PDFPeerPub: A Device for Concurrent Operant Oral Self-Administration by Multiple Rats.
eNeuro
January 2025
Department of Pharmacology, Addiction Science and Toxicology, University of Tennessee Health Science Center, Memphis, TN 38163 USA.
The social environment has long been recognized to play an important role in substance use, which is often modeled in rodents using operant conditioning. However, most operant chambers only accommodate one rodent at a time. We present PeerPub - a unique social operant chamber.
View Article and Find Full Text PDFDevelopment of a dual PM sampling and direct exposure system incorporated an in vitro air-liquid interface culture method: Application to the northern Thailand haze season.
Environ Pollut
December 2024
Biomedical Engineering Institute, Chiang Mai University, Chiang Mai, 50200, Thailand; Biomedical Engineering and Innovation Research Center, Chiang Mai University, Chiang Mai, 50200, Thailand. Electronic address:
Exposure to ambient air pollution is associated with several noncommunicable diseases, and it adversely affects the respiratory system and other organ systems. Several studies have investigated the underlying mechanisms of biological response to air pollutants using conventional techniques, but there is a lack of research on the effects of air pollution at the cellular level. This study developed a dual system that combines PM (particulate matter <2.
View Article and Find Full Text PDFManaging a Mental Disorder With New Technologies: TheLeadless Pacemaker in Reel's Syndrome, a Case Report.
Pacing Clin Electrophysiol
December 2024
Electrophysiology and Cardiac Pacing Unit, Pellegrini Hospital, Naples, Italy.
Reel's syndrome (RS) is an unusual cause of pacemaker lead dislodgement. We present the case of a 59-year-old female patient with Down syndrome (DS) implanted with a dual-chamber endovascular pacemaker due to symptomatic sinus node disfunction, reporting several syncopal episodes in last days and showing abnormal electrical parameters at the 2-months follow-up due to RS. The malfunctioning device was removed and an endocardial leadless pacing system was implanted.
View Article and Find Full Text PDFLeadless pacemaker implantation after delayed atrial lead perforation and battery depletion: a case report.
BMC Cardiovasc Disord
December 2024
Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Background: Delayed lead perforation is a rare complication of cardiac implantable electronic device (CIED). Clinical presentations range from completely asymptomatic to pericardial tamponade. Surgical lead extraction is recommended and transvenous lead extraction (TLE) with surgical backup is an alternative method.
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