A patient with a rare manifestation of phenytoin-induced hyperplasia is reported. Severe maxillary and mandibular gingival hyperplasia occurred prior to the eruption of the dentition and without evidence of any predisposing local irritation factors.
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Phenytoin-Induced Gingival Overgrowth with Predominant Involvement of Hard Palate and Floor of Oral Cavity: A Case Report and Review of Literature.
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Article Synopsis
- Drug-induced gingival overgrowth (DIGO) is a common condition caused by long-term use of phenytoin for seizures, often improving after stopping the medication.
- Typically, this overgrowth appears in the upper and lower jaw, especially in the front areas that are more exposed.
- This report highlights a unique case of phenytoin-induced gingival overgrowth predominantly affecting the hard palate and floor of the mouth, which is not found in existing English literature.
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Assistant Professor, Department of Dental Health, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia, Phone: +966500655550, e-mail:
Introduction: The aim of this report is to present a severe case of phenytoin (PHT)-induced gingival hyperplasia in a Saudi patient.
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