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Cellulose nanofibers gained increasing interest in the production of medical devices such as mucoadhesive nanohydrogels due to their ability to retain moisture (high hydrophilicity), flexibility, superior porosity and durability, biodegradability, non-toxicity, and biocompatibility. In this work, we aimed to compare the suitability of selected bacterial and vegetal nanocellulose to form hydrogels for biomedical applications. The vegetal and bacterial cellulose nanofibers were synthesized from brewer's spent grains (BSG) and kombucha membranes, respectively.

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Surgical treatment for severe endodontic-periodontal lesion: A case report with 2-year follow-up.

Clin Adv Periodontics

January 2025

Department of Periodontology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.

Background: Various surgical techniques have recently been developed for periodontal tissue regeneration, especially those do not involve any incisions in the interdental papillae at the regeneration site. These techniques have significant advantages for obtaining clinical attachment gain with least amount of gingival recession, however, may also have disadvantages such as limited field of surgical view, difficulty in debridement, and limited access only from the buccal side. This case report addresses a 2-year follow-up with a novel surgical approach to achieve periodontal regeneration that overcomes these limitations: the flexible tunnel technique (FTT).

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A photo-thermal dual crosslinked chitosan-based hydrogel membrane for guided bone regeneration.

Int J Biol Macromol

January 2025

Institute of Stomatology & Research Center of Dental Esthetics and Biomechanics, School and Hospital of Stomatology, Fujian Medical University, 246 Yangqiao Zhong Road, Fuzhou, Fujian 350002, China. Electronic address:

Alveolar bone defects caused by inflammation or trauma jeopardize patients' oral functions. Guided bone regeneration (GBR) is widely used in repairing periodontal tissue, with barrier membranes play a crucial role in preserving the bone regeneration space. In this study, an injectable dual-crosslinked hydrogel was developed to improve the existing barrier membranes in flexibility and functionality.

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Article Synopsis
  • An innovative toothbrush was created with a rotatable shank and a flexible design to improve access to all surfaces of the mouth, aimed at reducing plaque and improving gingival health.
  • A randomized controlled trial compared this rotatable shank toothbrush with traditional flexible and straight handle toothbrushes to see which was more effective for plaque control and gingival health outcomes.
  • Results showed that the rotatable shank toothbrush provided better improvements in plaque removal and gingival health compared to the other types of toothbrushes used in the study.
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Objectives: Platelet concentrates are biomaterials with significant potential in tissue regeneration, functioning as scaffolds with greater leukocyte inclusion and a flexible fibrin mesh. However these concentrates have different preparation methods and biological properties. The objective of this clinical investigation was to evaluate the effects of utilizing platelet-rich fibrin (PRF) materials (L-PRF and A-PRF) as a palatal bandage following free gingival graft (FGG) on patients' morbidity and oral health-related quality of life.

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