The separation in a sucrose gradient of the "myofibrillar" fraction of normal and autolysed muscle tissue gave 4 components. During the post-mortem destruction of the tissue there was observed a slight decrease of the "myofibrillar" fraction yield and also certain changes in the distribution of protein between different components. Under the selected conditions the RNA-ase activity was found in all 4 components. During the course of autolysis the enzymatic activity increased in the whole "myofibrillar" fraction, as well as in the lysosomal-mitochondrial components of "myofibrillae".
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