Based upon data available from the National Council on Alcoholism and encouraged by the emerging concept of alcoholism as a disease responsive to the multidisciplinary approach to its management, a program to assist alcoholic employees was instituted in 1968 at the United Airlines Maintenance Operations Center in San Francisco. This program was developed through the tripartite efforts of management, union and the medical department. Using this basic model, a similar effort to assist flight crew members of our San Francisco pilot domicile emerged in 1970. The method is oriented to the three-fold process of identification, referral for treatment, and followup. The mechanism of identification includes an intervention process. Treatment is accomplished in a specialty hospital embracing the principles of Alcoholics Anonymous. The essential monthly followup is continued for 2 years. Twenty-five pilots in United's system have been returned to flight deck duties after treatment and recertification.
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JMIR Form Res
January 2025
Sexual Health and Reproductive Equity Program, School of Social Welfare, University of California, Berkeley, Berkeley, CA, United States.
Background: Racial inequities in pregnancy outcomes persist despite investments in clinical, educational, and behavioral interventions, indicating that a new approach is needed to address the root causes of health disparities. Guaranteed income during pregnancy has the potential to narrow racial health inequities for birthing people and infants by alleviating financial stress.
Objective: We describe community-driven formative research to design the first pregnancy-guaranteed income program in the United States-the Abundant Birth Project (ABP).
Blood
January 2025
University of Chicago, Chicago, Illinois, United States.
Most diffuse large B-cell lymphoma (DLBCL) patients treated with immunotherapies such as bispecific antibodies (BsAb) or chimeric antigen receptor (CAR) T cells fail to achieve durable treatment responses, underscoring the need for a deeper understanding of mechanisms that regulate the immune environment and response to treatment. Here, an integrative, multi-omic approach was applied to multiple large independent datasets in order to characterize DLBCL immune environments, and to define their association with tumor cell-intrinsic genomic alterations and outcomes to CD19-directed CAR T-cell and CD20 x CD3 BsAb therapies. This approach effectively segregated DLBCLs into four immune quadrants (IQ) defined by cell-of-origin and immune-related gene set expression scores.
View Article and Find Full Text PDFPsychol Trauma
January 2025
Department of Medicine, Section of General Internal Medicine, University of Chicago.
Objective: From the beginning of the COVID-19 pandemic, there has been a proliferation of anti-Asian racism. In addition to being personal targets of racism, members of the Asian American community have also been vicariously exposed to repeated news and social media stories about anti-Asian racism. Emerging research suggests that vicarious exposure to racism during the pandemic is associated with decreased well-being, although mechanisms of action are not yet clear.
View Article and Find Full Text PDFPLoS One
January 2025
College of Medicine, University of Illinois Chicago, Chicago, IL, United States of America.
This study sheds light on how journalists respond to evolving debates within academia around topics including research integrity, improper use of metrics to measure research quality and impact, and the risks and benefits of the open science movement. It does so through a codebook thematic analysis of semi-structured interviews with 19 health and science journalists from the Global North. We find that journalists' perceptions of these academic controversies vary widely, with some displaying a highly critical and nuanced understanding and others presenting a more limited awareness.
View Article and Find Full Text PDFJAMA Neurol
January 2025
Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco.
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