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'Entanglement of nursing care': A theoretical proposition to understand the complexity of nursing work and division of labour.
Int J Nurs Stud
January 2025
NIHR Collaboration for Applied Research (Wessex), University of Southampton, Southampton, United Kingdom. Electronic address:
Ongoing challenges in the provision of care, driven by growing care complexity and nursing shortages, prompt us to reconsider the basis for efficient division of nursing labour. In organising nursing work, traditionally the focus has been on identifying nursing tasks that can be delegated to other less expensive and less highly educated staff, in order to make best use of scarce resources. We argue that nursing care activities are connected and intertwined.
View Article and Find Full Text PDFThe effectiveness of two doses of recombinant hepatitis E vaccine in response to an outbreak in Bentiu, South Sudan: a case-control and bias indicator study.
Lancet Infect Dis
January 2025
Geneva Centre for Emerging Viral Diseases, Geneva University Hospitals, Geneva, Switzerland; Médecins Sans Frontières, Geneva, Switzerland; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Division of Tropical and Humanitarian Medicine, Geneva University Hospitals, Geneva, Switzerland. Electronic address:
Background: Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, particularly in Asia and Africa, where HEV genotypes 1 and 2 are prevalent. Although a recombinant vaccine, Hecolin, is available, it has not been used to control outbreaks. The licensed three-dose regimen might pose challenges for it to be an impactful outbreak control tool.
View Article and Find Full Text PDFDecoding neuronal networks: A Reservoir Computing approach for predicting connectivity and functionality.
Neural Netw
December 2024
Department of Physics, University of Trento, Via Sommarive 14, Trento, 38123, TN, Italy.
In this study, we address the challenge of analyzing electrophysiological measurements in neuronal networks. Our computational model, based on the Reservoir Computing Network (RCN) architecture, deciphers spatio-temporal data obtained from electrophysiological measurements of neuronal cultures. By reconstructing the network structure on a macroscopic scale, we reveal the connectivity between neuronal units.
View Article and Find Full Text PDFFluvastatin, an HMG-CoA reductase inhibitor, exerts protective effect against NMDA-induced seizure by increasing the seizure threshold and modulating membrane excitability in embryonic rat cortical neuron.
Brain Res
December 2024
Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli, Taiwan.
Background: Epilepsy affects nearly 50 million people worldwide. Previous studies have indicated the neuroprotective effects of statin on several neuropathological conditions. However, it is very much unknown whether fluvastatin was able to alter the seizure types related to neuronal excitability and progression mediated by NMDA receptor activation, and the mechanisms involved in these actions are not completely understood so far.
View Article and Find Full Text PDFIodine transfer to dairy cow's milk: A revised biokinetic model.
J Hazard Mater
December 2024
Faculty of Biosciences, Norwegian University of Life Sciences, PO Box 5003, Ås N-1432, Norway.
A new biokinetic model for iodine in dairy cows was developed utilizing data from a 4 × 4 factorial feeding experiment with rumen-cannulated cows that were fed rapeseed cake containing substances known to influence iodine metabolism, and soybean meal without such effects. I was administered both intravenously and intra-ruminally to document metabolism pathways. The new model included compartments such as saliva and thyroid gland, often ignored in other models, and in contrast to previously available biokinetic models, it fitted well to our experimental data.
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