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Association Between Weight-Adjusted Waist Index and Cognitive Function in Older Adults Without Diabetes: A Cross-Sectional Study.
Clin Interv Aging
January 2025
Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People's Republic of China.
Background: This study investigates the correlation between the weight-adjusted waist index (WWI) and cognitive performance in the senior American population, focusing on those without diabetes from 2011 to 2014.
Methods: We analyzed data from the 2011-2012 and 2013-2014 National Health and Nutrition Examination Surveys (NHANES), focusing on non-diabetic participants aged 60 and older who completed cognitive tests: Establish a Registry for Alzheimer's disease (CERAD), the Animal Fluency test (AFT), and Digit Symbol Substitution test (DSST). WWI was calculated using waist circumference divided by the square root of body weight.
The role of vitamin K2 in cognitive impairment: linking vascular health to brain health.
Front Aging Neurosci
January 2025
Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.
Cognitive impairment, marked by a decline in essential mental aspects such as attention, memory, and problem-solving, is significantly correlated with advancing age. This condition presents a major challenge for the elderly, adversely affecting quality of life, diminishing independence, and imposing substantial burdens on healthcare systems. Recent research indicates that vitamin K2 may be vital for preserving brain health and cognitive function.
View Article and Find Full Text PDFST-CIRL: a reinforcement learning-based feature selection approach for enhanced anxiety classification.
Physiol Meas
January 2025
Department of Electronics and Communication , Delhi Technological University Department of Electronics and Communication, Delhi Technological university, Bawana, New Delhi-42, New Delhi, Delhi, 110042, INDIA.
A physiological signal-based Human-Computer Interaction (HCI) system provides a communication link between human emotional states and external devices. Accurately classifying these signals is vital for effective interaction, which requires extracting and selecting the most discriminative features to differentiate between various emotional states. This paper introduces the SMOTETomek-Correlated Interactive Reinforcement Learning (ST-CIRL) framework for anxiety classification, which leverages meta-descriptive statistics to enhance the state representation in the reinforcement learning process.
View Article and Find Full Text PDFRisks and rates, and the mathematical link between them.
Eur J Epidemiol
January 2025
Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, H3A 1G1, Canada.
The risk over a given time span can be calculated as one minus the exponentiated value of the negative of the integral of the incidence density function (or hazard rate function) over that time span. This relationship is widely used but, in the few instances where textbooks have presented it, the derivations of it tend to be purely mathematical. I first review the historical contexts, definitions, distinctions and links.
View Article and Find Full Text PDFThe urinary eccDNA landscape in prostate cancer reveals associations with genome instability and vital roles in cancer progression.
J Adv Res
January 2025
Department of Urology, Center for Regeneration and Aging, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu 322000 China. Electronic address:
Introduction: Extrachromosomal circular DNA (eccDNA) plays significant roles in cancer progression and prognosis. However, it remains unclear whether cell-free eccDNA, considered more stable than linear DNA, possesses cancer-specific genomic features. Furthermore, the biogenesis and function of eccDNAs are not yet fully understood.
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