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Causal associations between mobile phone usage and glaucoma risk: A Mendelian randomization study.
Medicine (Baltimore)
November 2024
Department of Ophthalmology Department, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Article Synopsis
- - Previous research suggests a potential link between mobile phone usage and glaucoma risk, prompting this study to investigate the causal relationship using a Mendelian randomization analysis.
- - The study utilized data from genome-wide association studies to assess how mobile phone usage might increase glaucoma risk, finding significant results that indicate a causal effect (ORIVW = 1.358, P = .019).
- - Findings highlight mobile phone usage as a modifiable risk factor for glaucoma, opening up new areas for research into the underlying mechanisms of this eye disorder.
Revisiting Diagnostic Criteria for Bilateral Vestibulopathy: A New Comprehensive Instrumental Model.
Audiol Res
November 2024
Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater University of Bologna, 40138 Bologna, Italy.
Bilateral vestibulopathy (BVP) is a disabling condition characterized by a deficit in vestibular function on both sides. Current diagnostic criteria consider instrumental data only from horizontal canals, excluding vertical canals and otolithic function, with the possibility of not including some variants of BVP. This study aims to evaluate vestibular functions in people with chronic vestibular syndrome through a comprehensive battery of tests.
View Article and Find Full Text PDFThe Role of Adjunctive Triamcinolone Acetonide in Post-traumatic Vitreoretinal Surgery: Current Insights and Future Perspectives.
Cureus
October 2024
Ophthalmology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Post-traumatic vitreoretinal surgery is pivotal for repairing damage to the retina and vitreous body, commonly resulting from blunt or penetrating ocular trauma. Incorporating adjunctive pharmacological agents, particularly triamcinolone acetonide (TA), has gained considerable prominence in optimizing surgical outcomes. TA, a potent corticosteroid, is applied intraoperatively to improve the visualization of vitreous structures and epiretinal membranes, enabling surgeons to perform more precise maneuvers.
View Article and Find Full Text PDFToxic epidermal necrolysis (TEN) is a severe, often drug-induced mucocutaneous reaction characterized by widespread epidermal necrosis and detachment. Ocular involvement is common and can lead to significant morbidity if not addressed promptly. This case report presents a 10-year-old female with fever, rash, and severe ocular symptoms.
View Article and Find Full Text PDFAssociations between Disc Hemorrhage and Primary Open-Angle Glaucoma Based on Genome-Wide Association and Mendelian Randomization Analyses.
Biomedicines
October 2024
Department of Ophthalmology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Article Synopsis
- - The study investigated genetic factors related to disc hemorrhage (DH) and its potential link to primary open-angle glaucoma (POAG) using data from 8,488 Koreans.
- - Significant single-nucleotide polymorphisms (SNPs) associated with DH were identified, with heritability estimated at 6.7%, but no genetic correlation with POAG was found.
- - Mendelian randomization analysis indicated there is no causal relationship between DH and POAG, suggesting that while DH is a risk factor, it may not directly cause POAG.
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