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Increase of cortical acetylcholine release after systemic administration of chlorophenylpiperazine in the rat: an in vivo microdialysis study.
Neurosci Lett
November 1997
Department of Pharmacology, Varna Medical University, Bulgaria.
The changes in acetylcholine (ACh) release from the cortex of freely moving rats after systemic administration of chlorophenylpiperazine (mCPP), a 5-HT2C agonist, were measured utilising microdialysis coupled to high performance liquid chromatography. mCPP administered intraperitoneally (i.p.
View Article and Find Full Text PDFRenin-angiotensin system in the antihypertensive effect of isoteoline in spontaneously hypertensive rats.
Clin Exp Pharmacol Physiol Suppl
December 1995
Department of Pharmacology, Faculty of Medicine, Higher Medical School, Sofia, Bulgaria.
1. The aim of the present study was to examine the effects of isoteoline (IST), a new tetrahydroaporphine derivative, on the blood pressure and some of the components of renin-angiotensin-aldosterone system (RAAS) in spontaneously hypertensive rats (SHR). 2.
View Article and Find Full Text PDFNeuropharmacological study of IST was carried out on mice and rats, using the so-called practically "blind" neuropharmacological screening of M. Nikolova and L. Daleva (1968).
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