In six anesthetized dogs 70 indicator-dilution curves and phase-plane plots were recorded. Indocyanine green was injected into the superior vena cava and sampled through a dichromatic cuvette densitometer from the femoral artery. Dye-dilution curves were recorded from dogs with normal cardiovascular systems and repeated after right-to-left shunts of different magnitude were surgically produced. The percent of blood shunting was calculated according to standard indicator-dilution equations and also by means of oximetric determination of blood samples. They were compared with shunt estimates based on phase-plane loop measurements. Good correlation was found with standard indicator-dilution procedures (r = 0.890) but not with oximetry (r = 0.466). The phase plane shows its utility in the detection and evaluation of small right-to-left shunts. These shunts affect the initial portion of the phase plane and the alterations appear to be more evident than in the corresponding concentration-vs.-time curves.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1152/ajpheart.1984.247.4.H517 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Short-term efficacy of right-to-left shunt closure in patients with vestibular migraine.
Front Neurol
December 2024
Department of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Objective: This study aims to evaluate the short-term efficacy of right-to-left shunt closure in vestibular migraine patients, and compare the efficacy between patent foramen ovale (PFO) closure and pulmonary arteriovenous malformation (PAVM) embolization. Additionally, the study identifies factors related to surgical outcomes.
Methods: Forty-one patients with vestibular migraine and medium to large right-to-left shunts underwent surgery: PFO closure, PAVM embolization, or both.
Is there any role for an atrial septal defect in off-loading a orderline left ventricle?
Interdiscip Cardiovasc Thorac Surg
December 2024
Division Head, cardiovascular Surgery, Hospital for Sick Children, Toronto, Director of Adult Congenital Heart Surgery, Toronto General Hospital ACHD Unit, and Professor, University of Toronto, Canada.
A_small_ASD_with right-to-left shunt is useful for off-loading a dysfunctional right ventricle postoperatively. However, an ASD with left-to-right shunt may not be as useful for a dysfunctional left ventricle. Experimental data is limited at present.
View Article and Find Full Text PDFFetal-to-Neonatal Transition of an Infant with Transposition of the Great Arteries and Intact Ventricular Septum: A Case Report.
Biomed Hub
December 2024
Division of Paediatric Cardiology, Department of Paediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.
Introduction: Transposition of the great arteries (TGA), especially with intact ventricular septum (TGA-IVS), presents unique challenges during fetal-to-neonatal transition, which can contribute to developing persistent pulmonary hypertension of the newborn (PPHN).
Case Presentation: A male newborn with TGA-IVS, delivered via caesarean section, presented with hypoxemia and tachycardia immediately after birth (preductal SpO: 50-60%, post-ductal SpO: 70-75%). Echocardiography revealed a floppy interatrial septum and two interatrial connections with bidirectional shunting.
Intraoperative Hemodynamic Instability in a Patient With Ebstein's Anomaly Complicated With Eisenmenger Syndrome.
Case Rep Cardiol
December 2024
Department of Anesthesiology and Pain Management, Cleveland Clinic, Cleveland, Ohio, USA.
Ebstein's anomaly is a rare congenital displacement of the tricuspid valve resulting in atrialization of the right ventricle. About half of the patients with Ebstein's anomaly also have atrial septal defects, which may lead to chronic shunting and development of Eisenmenger syndrome. We describe a case of a sexagenarian male patient with a history of Ebstein's anomaly complicated with Eisenmenger syndrome undergoing robotic laparoscopic adrenalectomy who presented hemodynamic instability, hypoxemia, and likely right-to-left shunting intraoperatively, as well as the actions taken to correct it and have a successful outcome.
View Article and Find Full Text PDFA Case of Pulmonary Arteriovenous Shunt Diagnosed by Microbubble Test via a Swan-Ganz Catheter.
Cureus
December 2024
Department of Cardiology, Japanese Red Cross Maebashi Hospital, Maebashi, JPN.
When encountering severe hypoxemia that does not respond to oxygen supplementation, it is essential to consider underlying right-to-left shunting. Among various diagnostic approaches, the microbubble test via transthoracic echocardiography (TTE) is a simple, noninvasive method for detecting pulmonary arteriovenous shunts, particularly in hepatopulmonary syndrome (HPS). Although microbubbles are usually administered peripherally, using a Swan-Ganz (SG) catheter to inject microbubbles directly into the pulmonary artery may provide even more definitive diagnostic information.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!