The cutaneous water loss was investigated in 12 patients affected with Basedow's disease by Evaporimeter Ep-1. The mean value of the CWL resulted 49,8 +/- 18,2 g/h. This result is significantly higher compared with the value of normal somali people equal to 25,24 +/- 14,6 g/h.
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Biomedicines
January 2025
I-MVET Research in Veterinary Medicine, Faculty of Veterinary Medicine, Lusófona University-Lisbon University Centre, 1749-024 Lisbon, Portugal.
Promoting rapid healing is a concern in skin wound treatment, as the increased pain and the loss of functional ability when wounds become chronic create a complex problem to manage. This scoping review aimed to explore the literature and synthesize existing knowledge on the therapeutic use of CO in treating cutaneous wounds. The literature was selected using previously defined inclusion and exclusion criteria, and 22 articles were selected for data extraction.
View Article and Find Full Text PDFEur J Pharm Biopharm
February 2025
BASF SE, Carl-Bosch-Strasse 38, 67056 Ludwigshafen am Rhein, Germany. Electronic address:
Poloxamer 338 is used as versatile thermo-responsive gelling agent in topical and sub-cutaneous applications. Due to application specific needs a gel point below body or even below room temperature is required. The influence of inorganic salts and active pharmaceutical ingredients (APIs) on the gel point was investigated using oscillatory rheology to identify the driving forces and predictors for gel point alteration.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Microbiology, College of Life Science, Key Laboratory for Agriculture Microbiology, Shandong Agricultural University, Tai'an 271018, PR China; School of Pharmacy, the Key Laboratory of Medical Antibacterial Materials of Shandong Province, Binzhou Medical University, Yantai 264003, PR China. Electronic address:
Chronic wounds caused by microbial infection have emerged as a major challenge on patients and medical health system. Bacterial cellulose (BC) characterized by its excellent biocompatibility and porous network, holds promise for addressing complex wound issues. However, lack of inherent antibacterial activity and cross-linking sites in the molecular network of BC have constrained its efficacy in hydrogel design and treatment of bacterial-infected wounds.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Department of Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.
Tissue engineering and regenerative medicine have made significant breakthroughs in creating complex three-dimensional (3D) constructs that mimic human tissues. This progress is largely driven by the development of hydrogels, which enable the precise arrangement of biomaterials and cells to form structures resembling native tissues. Gelatin-based bioinks are widely used in wound healing due to their excellent biocompatibility, biodegradability, non-toxicity, and ability to accelerate extracellular matrix formation.
View Article and Find Full Text PDFAAPS PharmSciTech
January 2025
Consulting, Fort Collins, Colorado, USA.
Continuously explored in pharmaceuticals, microemulsions and nanoemulsions offer drug delivery opportunities that are too significant to ignore, namely safe delivery of clinically relevant drug doses across biological membranes. Their effectiveness as drug vehicles in mucosal and (trans)dermal delivery is evident from the volume of published literature. Commonly, their ability to enhance skin permeation is attributed to dispersion size, a characteristic closely related to solubilization capacity.
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