There is increasing number of cases of acquired immune deficiency syndrome (AIDS) and in France there have been about 100 cases. The authors report one case who died within 10 months. The patient presented a Pneumocystis carinii pneumonia, extensive peri-anal herpes, gastro-intestinal candidiasis and, in the final stage, severe diarrhoea. In the context of this case, the authors review the principal manifestations of this new clinical entity.

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