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High prevalence of xerophthalmia linked to socio-demographic and nutritional factors among vitamin A-deficient rural primary schoolchildren in Malaysia.
Nutr Res
November 2024
Department of Ophthalmology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Article Synopsis
- * A study involving 596 schoolchildren aged 8-12 years revealed a high prevalence of xerophthalmia (48.8%), primarily identified by conjunctival xerosis, and linked to factors like malnutrition and socio-demographic status.
- * Boys and indigenous Orang Asli children showed a higher risk for xerophthalmia, while overweight/obese children had a lower risk, highlighting the need for targeted interventions to address VAD and its related health issues in these communities.
Corneal blindness in the developing world: The role of prevention strategies.
F1000Res
April 2024
Centre for Ocular Regeneration (CORE), Prof. Brien Holden Eye Research Centre, Champalimaud Translational Centre for Eye Research, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Corneal blindness is an important contributor to the burden of global blindness and has a greater prevalence in low-income countries of the developing world where resources and infrastructure are limited. The causes of corneal blindness too are different from high-income countries and include infectious keratitis, ocular trauma, and xerophthalmia. Persons with these indications tend to have unfavourable outcomes after corneal transplantation, limiting their chances of benefitting from this sight-saving procedure.
View Article and Find Full Text PDFImpact of home food production on nutritional blindness, stunting, wasting, underweight and mortality in children: a systematic review and meta-analysis of controlled trials.
Crit Rev Food Sci Nutr
March 2022
Norwich Medical School, University of East Anglia, Norwich, UK.
Vitamin A deficiency is highly prevalent and remains the major cause of nutritional blindness in children in low-and middle-income countries, despite supplementation programmes. Xeropthalmia (severe drying and thickening of the conjunctiva) is caused by vitamin A deficiency and leads to irreversible blindness. Vitamin A supplementation programmes effectively reduce vitamin A deficiency but many rural children are not reached.
View Article and Find Full Text PDFPrevalence and determinants of xerophthalmia in rural children of Uttarpradesh, India.
Nepal J Ophthalmol
March 2015
Introduction: Vitamin A deficiency (VAD) is recognized as a major cause of blindness among children in India.
Objective: To find out the prevalence of VAD in rural children of Uttar Pradesh, India.
Materials And Methods: This cross-sectional study was undertaken amongst children (0-15 years) in a rural area of Bareilly (Uttar Pradesh) where the study population was selected by simple random sampling out of villages under a Primary Health Centre.
Prevalence of vitamin A deficiency in pregnant and lactating women in the Republic of Congo.
J Health Popul Nutr
March 2013
Service des Maladies tropicales, Hospital Saint André, University Hospital Center of Bordeaux, Centre René Labusquière (Tropical Diseases Branch), EA 3677, University Victor Segalen Bordeaux 2, F-33076 Bordeaux, France.
Vitamin A status in a sample of pregnant and lactating women living in several representative regions of Congo was assessed and compared between August and September 2004. This survey was conducted using a randomized two-stage cluster-sampling method with stratification on 90 clusters, each consisting of at least 15 women. Vitamin A status was determined in a total of 1,054 individuals, using the impression cytology with transfer (ICT) test, the modified relative dose response test (MRDR test) on dried blood spots (DBS), and clinical examination to detect signs of xerophthalmia.
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