One case with acute interstitial nephritis with undistinguished etiology, accompanied by iridocyclitis is described. Recently, numerous communications about similar cases have been reported which justify the differentiation of the syndrome "interstitial nephritis-iridocyclitis" among the acute interstitial nephritis. The case is of certain interest because of some characteristics: involvement of liver in the morbid process, immunemorphological finding from that described by other authors. Assumptions are presented about the pathogenetic mechanism of the disease. Conclusions are drawn in connection with the corticosteroid treatment, having induced a considerable improvement.

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