A check up of literature has been made concerning the congenital microspherocytic hemolytic anemia, reporting of some new data about the pathogenesis of the disease. One family is described with CMHA--one father and his two daughters, the two children of his first daughter and the only child of the second daughter, hence confirming the familial character of the disease. All patients have been splenectomized. After the splenectomy they are practically healthy, without hemolytic crises, supporting the statement that splenectomy is the treatment of choice in CMHA therapy.
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The article presents an observation of a 63-year-old female patient suffering from arterial hypertension, coronary artery disease complicated by a persistent form of atrial fibrillation during 1.5 months, and hereditary Minkowski-Chauffard hemolytic anemia. Treatment with cordaron proved to be ineffective, while oral administration of quinidin in a dose of 1 gr (0.
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View Article and Find Full Text PDF[Long term complications of splenic artery ligation for haematologic problems in the child. A study of 7 cases].
Chir Pediatr
May 1990
Service Chirurgie Pédiatrique, Hôtel-Dieu, Clermont-Ferrand.
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