In 110 patients with different malignant tumors various pharmacological substances (Ridol (G. Richter, Hungary), Arphonad (Hoffmann, Switzerland), Xavin (Chinoin, Hungary) etc.) were used in lymphography to improve inflow of contrast medium and visualization of lymph vessels and nodes. Different substances with vasodilatatory effects of varying degree were tested. Ridol and the combination Atropin-Promedol-Pipolphen proved to have a specific lymphotropic affinity. Time of contrast medium injection could be shortened and visualization of the intermediary lymphnode sinus as well as thoracic duct improved by pharmacolymphography. The optimal method consists of i.m. Ridol application 10 to 15 minutes prior to lymphangiography and endolymphatic injection of the combination Atropin-Promedol-Pipolphen.
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