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MAO-B-triggered reaction for an optical triple-signal assay and AND logic gate application based on PEI-functionalized silver nanoparticles.
Mikrochim Acta
January 2025
School of Pharmacy, Lanzhou University, Lanzhou, 730000, P. R. China.
A novel analytical method was designed and developed that exhibited ultraviolet-visible (UV-Vis), fluorescence (FL), and resonance Rayleigh scattering (RRS) signals for straightforward and comprehensive determination of monoamine oxidase B (MAO-B) using polyethylenimine-functionalized silver nanoparticles (PEI-Ag NPs). Through a facile one-step experiment, and NaOH assisted, in an aqueous solution of 100 ℃ for 40 min PEI reacted with AgNO to generate PEI-Ag NPs with a yellow color and weak blue fluorescence. Interestingly, phenylacetaldehyde (PAA), a specific product of MAO-B, causes significant enhancement of the three optical signals of UV-Vis, FL, and RRS.
View Article and Find Full Text PDFThreshold crossing time theory for quasicycles with application to brain rhythms.
Phys Rev E
October 2024
Department of Physics, University of Ottawa, Ottawa, Ontario, Canada K1N 6N5.
The amplitude of a two-dimensional Ornstein-Uhlenbeck colored noise process evolves according to the one-dimensional Rayleigh process. This is a general model for the random amplitude fluctuations of a quasicycle, i.e.
View Article and Find Full Text PDFCore-Satellite Nanoassemblies as SPR/SERS Dual-Mode Plasmonic Sensors for Sensitively Detecting Ractopamine in Complex Media.
J Agric Food Chem
December 2023
China Light Industry Key Laboratory of Meat Microbial Control and Utilization, School of Food and Biological Engineering, Engineering Research Center of Bio-process, Ministry of Education, Hefei University of Technology, Hefei 230009, P. R. China.
Article Synopsis
- A new dual-mode plasmonic sensor combining surface plasmon resonance and surface-enhanced Raman scattering has been developed for detecting ractopamine, a growth-promoting feed additive often abused illegally.
- This sensor utilizes core-satellite nanoassemblies that change properties when ractopamine is present, resulting in noticeable shifts in both color and intensity measurable through microscopy.
- It demonstrated high sensitivity with a detection limit of 0.03 ng/mL and offers practical applications for monitoring β-agonists, enhancing animal welfare, and ensuring market regulations with a portable device.
Rapid measurement and machine learning classification of colour vision deficiency.
Ophthalmic Physiol Opt
November 2023
Department of Psychology, Northeastern University, Boston, Massachusetts, USA.
Colour vision deficiencies (CVDs) indicate potential genetic variations and can be important biomarkers of acquired impairment in many neuro-ophthalmic diseases. However, CVDs are typically measured with tests which possess high sensitivity for detecting the presence of a CVD but do not quantify its type or severity. In this study, we introduce Foraging Interactive D-prime (FInD), a novel computer-based, generalisable, rapid, self-administered vision assessment tool and apply it to colour vision testing.
View Article and Find Full Text PDFRapid measurement and machine learning classification of color vision deficiency.
medRxiv
June 2023
Department of Psychology, Northeastern University, USA.
Color vision deficiencies (CVDs) indicate potential genetic variations and can be important biomarkers of acquired impairment in many neuro-ophthalmic diseases. However, CVDs are typically measured with insensitive or inefficient tools that are designed to classify dichromacy subtypes rather than track changes in sensitivity. We introduce FInD (Foraging Interactive D-prime), a novel computer-based, generalizable, rapid, self-administered vision assessment tool and applied it to color vision testing.
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