Long-term hypokinesia of August and Wistar Albino Glasgow rats caused some alterations in composition of total lipids and cholesterol esters both in blood serum and in individual lipoprotein fractions. The most distinct alterations were the following ones: I. increase in content of very low density lipoproteins (VLDL) and of low density lipoproteins (LDL), 2. decrease in the level of cholesterol esters in blood serum with a simultaneous increase of their content in VLDL and LDL as well as with alteration of their composition, 3. decrease of triglyceride content in VLDL and increase--in LDL, exhibiting the alteration in activity of lipolytic enzymes. Functional activity of muscles was very important for maintaining of the normal level of blood serum lipids and lipoproteins.
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